(±)-α-生育酚磷酸二钠盐

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[1]. Saleh MM, et al. The photoprotective properties of α-tocopherol phosphate against long-wave UVA1 (385 nm) radiation in keratinocytes in vitro. Sci Rep. 2021 Nov 17;11(1):22400.

[2]. Wu Z, et al. α-Tocopherol, especially α-tocopherol phosphate, exerts antiapoptotic and angiogenic effects on rat bone marrow-derived endothelial progenitor cells under high-glucose and hypoxia conditions. J Vasc Surg. 2018 Apr;67(4):1263-1273.e1.

1.疏水参数计算参考值（XlogP）:无

2.氢键供体数量:2

3.氢键受体数量:5

4.可旋转化学键数量:14

5.互变异构体数量:无

6.拓扑分子极性表面积76

7.重原子数量:36

8.表面电荷:0

9.复杂度:664

10.同位素原子数量:0

11.确定原子立构中心数量:0

12.不确定原子立构中心数量:3

13.确定化学键立构中心数量:0

14.不确定化学键立构中心数量:0

15.共价键单元数量:2

Bioorg. Med. Chem. 19 , 6348-55, (2011)

The water-soluble vitamin E derivative, sodium dl-α-tocopheryl-6-O-phosphate (1), exhibits protective effects against skin damage. As reported herein, we investigated the actions of 1 on the formation…

Mol. Nutr. Food. Res. 54(5) , 588-98, (2010)

Vitamin E is known as the most important lipid antioxidant and is widely used to prevent age-associated diseases. Despite increasing knowledge about human vitamin E metabolism, little is known to just…

Free Radic. Biol. Med. 51(9) , 1643-55, (2011)

α-Tocopherol (α-TOH), a dietary component of vitamin E, is well known for its antioxidant capacity. Nevertheless, recent studies have pointed out non-anti-radical properties including cellular and gen…