描述 |
Dihydrokavain是一天然化合物,抗焦虑活性。 |
||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
相关类别 |
|
||||||||||||
溶解度 |
体外:
在DMSO中10mM
|
||||||||||||
储备液 |
|
||||||||||||
存储 |
请将产品存放在分析证书中的建议条件下。
|
||||||||||||
运输 |
室温;可能会有所不同 |
||||||||||||
SMILES |
O=C1C=C(OC)C[C@H](CCC2=CC=CC=C2)O1 |
||||||||||||
参考文献 |
|
||||||||||||
相关活性 小分子 |
磺丁醚-beta-环糊精 | 环孢菌素 | 2,7-二氯二氢代荧光黄二醋酸 | 1-甲基-4-苯基-1,2,3,6-四氢吡啶盐酸盐 | 4′,4”-双-2-咪唑啉-2-基对苯二丙烯酰苯胺二盐酸盐 | 乙莫克舍 | TD139 | Mitoquinone甲磺酸盐 | GSK2795039 | 5,5’,6,6’-四氯-1,1’,3,3’-四乙基苯并咪唑羰花青碘化物 | 胞内钙荧光探针 BAPTA-AM | AP20187 | GKT137831 | D-虫荧光素游离酸 | 野百合碱 |
密度 | 1.1±0.1 g/cm3 |
---|---|
沸点 | 413.6±45.0 °C at 760 mmHg |
熔点 | 56-60?C |
分子式 | C14H16O3 |
分子量 | 232.275 |
闪点 | 175.6±23.3 °C |
精确质量 | 232.109940 |
PSA | 35.53000 |
LogP | 1.95 |
外观性状 | 白色粉末 |
蒸汽压 | 0.0±1.0 mmHg at 25°C |
折射率 | 1.544 |
计算化学 |
1.疏水参数计算参考值(XlogP):2.8 2.氢键供体数量:0 3.氢键受体数量:3 4.可旋转化学键数量:4 5.互变异构体数量:无 6.拓扑分子极性表面积:35.5 7.重原子数量:17 8.表面电荷:0 9.复杂度:290 10.同位素原子数量:0 11.确定原子立构中心数量:0 12.不确定原子立构中心数量:1 13.确定化学键立构中心数量:0 14.不确定化学键立构中心数量:0 15.共价键单元数量:1 |
二氢醉椒素毒性英文版
|
危险品运输编码 | NONH for all modes of transport |
---|
Interaction of various Piper methysticum cultivars with CNS receptors in vitro. Planta Med. 67(4) , 306-11, (2001)
Methanolic leaf and root extracts of the Hawaiian kava (Piper methysticum Forst.) cultivars, Mahakea, Nene, Purple Moi and PNG, were tested on binding affinities to CNS receptors including GABAA (GABA…
|
|
Determination of six kavalactones in dietary supplements and selected functional foods containing Piper methysticum by isocratic liquid chromatography with internal standard. J. AOAC Int. 88(1) , 16-25, (2005)
Kava (Piper methysticum) dietary products have been sold worldwide for treatment of nervous anxiety, tension, and restlessness. Recent reports showed potential association of kava usage and liver inju…
|
|
Glial dysfunction in the mouse habenula causes depressive-like behaviors and sleep disturbance. J. Neurosci. 34(49) , 16273-85, (2014)
The lateral habenula (LHb) regulates the activity of monoaminergic neurons in the brainstem. This area has recently attracted a surge of interest in psychiatry because studies have reported the pathol…
|
|
2H-Pyran-2-one, 5,6-dihydro-4-methoxy-6-(2-phenylethyl)- |
4-Methoxy-6-(2-phenylethyl)-5,6-dihydro-2H-pyran-2-one |
Dihydrokavain |
dihydrokawain |
2H-Pyran-2-one, 5,6-dihydro-4-methoxy-6- (2-phenylethyl)-, (S)- |
(6S)-4-Methoxy-6-(2-phenylethyl)-5,6-dihydro-2H-pyran-2-one |
5,6-Dihydro-4-methoxy-6-(2-phenylethyl)-2H-pyran-2-one |
2H-Pyran-2-one, 5,6-dihydro-4-methoxy-6-(2-phenylethyl)-, (6S)- |