他唑巴坦钠

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中文名	他唑巴坦钠
英文名	tazobactam sodium
中文别名	[2S-(2a,3b,5a)]-3-甲基-7-氧代-3-(1H-1,2,3-三氮唑-1-基甲基)-4-硫代-1-氮杂双环[3,2,0]庚烷-2-羧酸钠 4,4-二氧化物 \| 泰唑巴坦钠
英文别名	更多

描述	Tazobactam sodium 是 β-内酰胺酶抑制剂类抗生素。Ceftolozane 与Tazobactam 联合应用，可提高头孢噻嗪对多种产 ESBL 肠杆菌科和部分类杆菌属的抗菌活性。
相关类别	研究领域 >> 感染信号通路 >> 抗感染 >> 细菌
SMILES	C[C@]([C@@H](N1[C@@]2([H])CC1=O)C(O[Na])=O)([S]2(=O)=O)CN3C=CN=N3
参考文献	[1]. Giacobbe DR, et al. Ceftolozane/tazobactam: place in therapy. Expert Rev Anti Infect Ther. 2018;16(4):307‐320.

密度	1.92 g/cm3
沸点	707.1?C at 760 mmHg
熔点	140-147?C
分子式	C₁₀H₁₁N₄NaO₅S
分子量	322.27300
闪点	381.4?C
精确质量	322.03500
PSA	133.67000
储存条件	Store at 0-5°C
水溶解性	H2O: 50?mg/mL, clear, colorless

他唑巴坦钠毒性英文版

个人防护装备	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
危害码 (欧洲)	Xi
风险声明 (欧洲)	36/37/38
安全声明 (欧洲)	S22-S24/25
危险品运输编码	NONH for all modes of transport
WGK德国	3
RTECS号	XI0191500
海关编码	2934999090

他唑巴坦二苯甲酯

89789-07-1

他唑巴坦钠

89785-84-2

文献：Journal of Medicinal Chemistry, , vol. 30, # 8 p. 1469 – 1474

他唑巴坦

89786-04-9

哌拉西林

61477-96-1

哌拉西林钠

59703-84-3

他唑巴坦钠

89785-84-2

文献：EP1759697 A1, ; Page/Page column 2-3 ;

他唑巴坦钠上游产品? 3
CAS号89789-07-1 他唑巴坦二苯甲酯 CAS号89786-04-9 他唑巴坦 CAS号61477-96-1 哌拉西林
他唑巴坦钠下游产品? 0

他唑巴坦钠上游产品? 3

CAS号89789-07-1
他唑巴坦二苯甲酯

CAS号89786-04-9
他唑巴坦

CAS号61477-96-1
哌拉西林

他唑巴坦钠下游产品? 0

海关编码	2934999090
中文概述	2934999090. 其他杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Quantification of piperacillin, tazobactam, cefepime, meropenem, ciprofloxacin and linezolid in serum using an isotope dilution UHPLC-MS/MS method with semi-automated sample preparation.

Clin. Chem. Lab Med. 53(5) , 781-91, (2015)

Recent studies have demonstrated highly variable blood concentrations of piperacillin, tazobactam, cefepime, meropenem, ciprofloxacin and linezolid in critically ill patients with a high incidence of …

DrugBank 3.0: a comprehensive resource for ‘omics’ research on drugs.

Nucleic Acids Res. 39 , D1035-41., (2011)

DrugBank (https://www.drugbank.ca) is a richly annotated database of drug and drug target information. It contains extensive data on the nomenclature, ontology, chemistry, structure, function, action, …

Variable susceptibility to piperacillin/tazobactam amongst Klebsiella spp. with extended-spectrum beta-lactamases.

J. Antimicrob. Chemother. 51 , 605-612, (2003)

MICs of piperacillin/tazobactam are conventionally determined by varying the concentration of piperacillin in the presence of a fixed 4 mg/L tazobactam. When tested in this way, the MIC distribution f…

4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3-methyl-7-oxo-3-(1H-1,2,3-triazol-1-ylmethyl)-, 4,4-dioxide, sodium salt, (2S,3S,5R)-

4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 3-methyl-7-oxo-3-(1H-1,2,3-triazol-1-ylmethyl)-, 4,4-dioxide, sodium salt, (2S,3S,5R)-

Sodium (2S,3S,5R)-3-methyl-7-oxo-3-(1H-1,2,3-triazol-1-ylmethyl)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate 4,4-dioxide

(2S,3S,5R)-3-méthyl-7-oxo-3-(1H-1,2,3-triazol-1-ylméthyl)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate-4,4-dioxyde de sodium

Tazobactam Sodium

MFCD00917472

Sodium (2S,3S,5R)-3-methyl-7-oxo-3-(1H-1,2,3-triazol-1-ylmethyl)-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylate, 4,4-dioxide

[2S-(2a,3b,5a)]-3-Methyl-7-oxo-3-(1H-1,2,3-triazol-1-ylmethyl)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 4,4-dioxide sodium salt

4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3-methyl-7-oxo-3-(1H-1,2,3-triazol-1-ylmethyl)-, 4,4-dioxide, sodium salt, (2S,3S,5R)- (1:1)

Tazobactam sodium salt

CL 307,579

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他唑巴坦钠

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