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刺五加苷

刺五加苷

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?刺五加苷名称


















中文名

刺五加苷
英文名

Syringin
中文别名


紫丁香酚苷




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紫丁香酚甙




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刺五加苷B




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紫丁香苷



英文别名
更多





?刺五加苷生物活性


































描述
Syringin 是 Acanthopanax senticosus 中主要的一种生物活性酚苷类物质,具有抗骨质疏松的作用。Syringin 通过抑制自噬来防止压力超载引起的心肌肥厚。
相关类别



SMILES

O[C@H]([C@@H](O)[C@@H]1O)[C@@H](O[C@@H]1CO)OC(C(OC)=CC(/C=C/CO)=C2)=C2OC
参考文献

[1]. Liu J, et al. Syringin prevents bone loss in ovariectomized mice via TRAF6 mediated inhibition of NF-κB and stimulation of PI3K/AKT. Phytomedicine. 2018 Mar 15;42:43-50.

[2]. Li F, et al. Syringin prevents cardiac hypertrophy induced by pressure overload through the attenuation of autophagy. Int J Mol Med. 2017 Jan;39(1):199-207.







?刺五加苷物理化学性质













































密度 1.4±0.1 g/cm3
沸点 642.6±55.0 °C at 760 mmHg
熔点 192°C
分子式 C17H24O9
分子量 372.367
闪点 342.4±31.5 °C
精确质量 372.142029
PSA 138.07000
LogP -1.94
蒸汽压 0.0±2.0 mmHg at 25°C
折射率 1.623
储存条件 2-8°C
分子结构

1、 摩尔折射率:92.74

2、 摩尔体积(cm3/mol):263.0

3、 等张比容(90.2K):730.2

4、 表面张力(dyne/cm):59.4

5、 极化率(10-24cm3):36.76

计算化学

1.疏水参数计算参考值(XlogP):无

2.氢键供体数量:5

3.氢键受体数量:9

4.可旋转化学键数量:7

5.互变异构体数量:无

6.拓扑分子极性表面积138

7.重原子数量:26

8.表面电荷:0

9.复杂度:432

10.同位素原子数量:0

11.确定原子立构中心数量:5

12.不确定原子立构中心数量:0

13.确定化学键立构中心数量:1

14.不确定化学键立构中心数量:0

15.共价键单元数量:1






?刺五加苷安全信息




















安全声明 (欧洲)
24/25
危险品运输编码 NONH for all modes of transport
海关编码 2932999099


















?刺五加苷海关















海关编码 2932999099
中文概述 2932999099. 其他仅含氧杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素 品名, 成分含量, 用途
Summary 2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%








?刺五加苷文献27

更多文献














[Simultaneous determination of five glycosides in Aidi injection by RP-HPLC-ELSD].

Zhongguo Zhong Yao Za Zhi 36(6) , 706-8, (2011)

To develop a RP-HPLC-ELSD method for the simultaneous determination of five glycosides in Aidi injection.The separation was carried out at 35 degrees C on a Kromasil C18 column (4.6 mm x 250 mm, 5 mic…





Active components from Siberian ginseng (Eleutherococcus senticosus) for protection of amyloid β(25-35)-induced neuritic atrophy in cultured rat cortical neurons.

J. Nat. Med. 65(3-4) , 417-23, (2011)

Not only neuronal death but also neuritic atrophy and synaptic loss underlie the pathogenesis of Alzheimer’s disease as direct causes of the memory deficit. Extracts of Siberian ginseng (the rhizome o…





[Chemical constituents from Exochorda racemosa].

Zhongguo Zhong Yao Za Zhi 36(9) , 1198-201, (2011)

To study the chemical constituents of Exochorda racemosa.Compounds were isolated and purified by silica gel, Sephadex LH-20, MCI gel and RP-18 column chromatography, and their structures were determin…









?刺五加苷英文别名
















β-D-Glucopyranoside, 4-(3-hydroxy-1-propenyl)-2,6-dimethoxyphenyl


Sinapyl 4-O-β-D-glucopyranoside alcohol


4-[(1E)-3-Hydroxy-1-propen-1-yl]-2,6-dimethoxyphenyl β-D-glucopyranoside


4-[(1E)-

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