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刺五加苷E

刺五加苷E

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?刺五加苷E名称


















中文名

刺五加甙 E
英文名

Eleutheroside E
中文别名


刺五加甙E




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刺五加苷E,五加苷E




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刺五加苷E




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刺五加苷E




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五加苷E




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刺五加苷 E




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刺五加甙



英文别名
更多





?刺五加苷E生物活性












































描述
刺五加苷E (Eleutheroside E)是刺五加的重要成分,具有抗炎,保护缺血心脏的作用。
相关类别




溶解度

体外:

DMSO:≥7.5mg / mL(10.10 mM)

* “≥”表示可溶,但饱和度未知。


储备液

1 mM 1.3464 mL 6.7320 mL 13.4640 mL
5 mM 0.2693 mL 1.3464 mL 2.6928 mL
10 mM 0.1346 mL 0.6732 mL 1.3464 mL


存储

粉末 -20°C 3年
? 4°C 2年
在溶剂中 -80°C 6月
? -20°C 1月


运输

室温;可能会有所不同
SMILES

COC(C=C1[C@H]2[C@@](CO[C@@H]3C4=CC(OC)=C(O[C@@H]([C@@H]([C@@H](O)[C@@H]5O)O)O[C@@H]5CO)C(OC)=C4)([H])[C@]3([H])CO2)=C(C(OC)=C1)O[C@@H]([C@@H]([C@@H](O)[C@@H]6O)O)O[C@@H]6CO
参考文献

[1]. Chunyan He, et al. Eleutheroside E Ameliorates Arthritis Severity in Collagen-Induced Arthritis Mice Model by Suppressing Inflammatory Cytokine Release. Inflammation, Vol. 37, No. 5, October 2014 (# 2014)

[2]. Jiyun Ahn, et al. Eleutheroside E, An Active Component of Eleutherococcus senticosus, Ameliorates Insulin Resistance in Type 2 Diabetic db/db Mice. Evid Based Complement Alternat Med. 2013; 2013: 934183.


相关活性
小分子




磺丁醚-beta-环糊精



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环孢菌素



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2,7-二氯二氢代荧光黄二醋酸



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1-甲基-4-苯基-1,2,3,6-四氢吡啶盐酸盐



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4′,4”-双-2-咪唑啉-2-基对苯二丙烯酰苯胺二盐酸盐



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乙莫克舍



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TD139



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Mitoquinone甲磺酸盐



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GSK2795039



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5,5’,6,6’-四氯-1,1’,3,3’-四乙基苯并咪唑羰花青碘化物



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胞内钙荧光探针 BAPTA-AM



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AP20187



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GKT137831



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D-虫荧光素游离酸



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野百合碱






?刺五加苷E物理化学性质











































密度 1.5±0.1 g/cm3
沸点 935.7±65.0 °C at 760 mmHg
熔点 255 – 260?C
分子式 C34H46O18
分子量 742.718
闪点 519.7±34.3 °C
精确质量 742.268433
PSA 254.14000
LogP -3.91
外观性状 无色微结晶粉末
蒸汽压 0.0±0.3 mmHg at 25°C
折射率 1.616
储存条件 2-8°C






?刺五加苷E安全信息




























符号

GHS07


GHS07
信号词
Warning
危害声明
H302
危害码 (欧洲)
Xn
风险声明 (欧洲)
22
安全声明 (欧洲)
24/25
危险品运输编码 NONH for all modes of transport














?刺五加苷E文献15

更多文献














[Studies on chemical constituents from stem barks of Fraxinus paxiana].

Zhongguo Zhong Yao Za Zhi 33(16) , 1990-3, (2008)

To investigate the chemical constituents of Fraxinus paxiana.The chemical constituents were isolated and purified by chromatographic techniques and the structures of the compounds were identified with…





[Chemical constituents from flowers of Chrysanthemum indicum].

Zhongguo Zhong Yao Za Zhi 35(6) , 718-21, (2010)

To investigate the chemical constituents of the flowers of Chrysanthemum indicum.The chemical constituents were isolated by various column chromatographic methods. The structures were identified by sp…





[Studies on phenylpropanoids from herbs of Eriophyton wallichii].

Zhongguo Zhong Yao Za Zhi 33(22) , 2636-9, (2008)

To study the chemical constituents of Eriophyton wallichii.Compounds were separated and purified by column chromatographic methods, and their structures were elucidated by spectroscopic methods.Eight …









?刺五加苷E英文别名
























4-{(1R,3aR,4S,6aS)-4-[4-(β-L-Glucopyranosyloxy)-3,5-dimethoxyphenyl]tetrahydro-1H,3H-furo[3,4-c]furan-1-yl}-2,6-dimethoxyphenyl β-D-glucopyranoside


β-D-Glucopyranoside, 4-[(1R,3aR,4S,6aS)-4-[4-(β-L-glucopyranosyloxy)-3,5-dimethoxyphenyl]tetrahydro-1H,3H-furo[3,4-c]furan-1-yl]-2,6-dimethoxyphenyl


β-D-Glucopyranoside, 4-[(1R,3aS,4S,6aR)-4-[4-(β-L-glucopyranosyloxy)-3,5-dimethoxyphenyl]tetrahydro-1H,3H-furo[3,4-c]furan-1-yl]-2,6-dimethoxyphenyl


(2R,3S,4R,5R,6S)-2-[4-[6-[3,5-dimethoxy-4-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]-1,3,3a,4,6,6a-hexahydrofuro[3,4-c]furan-3-yl]-2,6-dimethoxyphenoxy]-6-(hydroxymethyl)oxane-3,4,5-triol


4-{(1R,3aS,4S,6aR)-4-[4-(β-L-Glucopyranosyloxy)-3,5-dimethoxyphenyl]tetrahydro-1H,3H-furo[3,4-c]furan-1-yl}-2,6-dimethoxyphenyl β-D-glucopyranoside








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