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| 描述 |
Desonide是非氟化皮质类固醇抗炎剂，能作用于糖皮质激素受体。 |
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| 相关类别 |
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| 溶解度 |
体外：
在DMSO中10mM
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| 储备液 |
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| 存储 |
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| 运输 |
室温;可能会有所不同 |
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| SMILES |
C[C@@]12[C@@]3(C(CO)=O)[C@@](OC(C)(O3)C)([H])C[C@@]1([H])[C@]4([H])CCC5=CC(C=C[C@]5(C)[C@@]4([H])[C@@H](O)C2)=O |
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| 参考文献 |
[3]. Parish, D. and N. Scheinfeld, Desonide foam: a review. Drugs Today (Barc), 2008. 44(1): p. 55-62.
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| 相关活性 小分子 |
氢化可的松 | 米非司酮 | 皮质酮 | 泼尼松 | 原人参三醇 | 氟替卡松丙酸酯 | 曲安西龙 | 可的松 | AL 082D06 | 糖皮质激素受体激动剂 | Mapracorat | 环索奈德 | 丙酸倍氯米松 | 丙酸氯倍他索 | Cort108297 |
| 密度 | 1.3±0.1 g/cm3 |
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| 沸点 | 580.1±50.0 °C at 760 mmHg |
| 熔点 | 274 – 275?C |
| 分子式 | C24H32O6 |
| 分子量 | 416.507 |
| 闪点 | 196.9±23.6 °C |
| 精确质量 | 416.219879 |
| PSA | 93.06000 |
| LogP | 2.62 |
| 外观性状 | 固体;White to Almost white powder to crystal |
| 蒸汽压 | 0.0±3.7 mmHg at 25°C |
| 折射率 | 1.598 |
| 储存条件 | Refrigerator |
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地索奈德毒性英文版
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| 危险品运输编码 | NONH for all modes of transport |
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| 海关编码 | 2937210000 |
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~%
地索奈德
638-94-8
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文献：Journal of the American Chemical Society, , vol. 81, p. 4573 |
| 海关编码 | 2937210000 |
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Prednacinolone |
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(4aR,4bS,5S,6aS,6bS,9aR,10aS,10bS)-5-hydroxy-6b-(hydroxyacetyl)-4a,6a,8,8-tetramethyl-4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-2H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-2-one |
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16a,17a-Isopropylidenedioxyprednisolone |
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2H-naphth[2',1':4,5]indeno[1,2-d][1,3]dioxol-2-one, 4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-5-hydroxy-6b-(hydroxyacetyl)-4a,6a,8,8-tetramethyl-, (4aR,4bS,5S,6aS,6bS,9aR,10aS,10bS)- |
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Desowen |
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2H-Naphth[2',1':4,5]indeno[1,2-d][1,3]dioxol-2-one, 4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-5-hydroxy-6b-(2-hydroxyacetyl)-4a,6a,8,8-tetramethyl-, (4aR,4bS,5S,6aS,6bS,9aR,10aS,10bS)- |
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Locapred |
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Desonide |
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(4aR,4bS,5S,6aS,6bS,9aR,10aS,10bS)-5-hydroxy-6b-(hydroxyacétyl)-4a,6a,8,8-tétraméthyl-4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodécahydro-2H-naphto[2',1':4,5]indéno[1,2-d][1,3]dioxol-2-one |
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Sterax |
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11b,16a,17,21-Tetrahydroxypregna-1,4-diene-3,20-dione Cyclic 16,17-Acetal with Acetone |
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16a-Hydroxy-D1-hydrocortisone-16a,17a-acetonide |
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16a-Hydroxyprednisolone-16a,17-acetonide |
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Steroderm |
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16a-Hydroxyprednisolone Acetonide |
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TRIDESILON |
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desonidum [INN_la] |
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MFCD00866151 |
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11β,16α,17,21-Tetrahydroxypregna-1,4-diene-3,20-dione cyclic 16,17-acetal with acetone |
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(4aR,4bS,5S,6aS,6bS,9aR,10aS,10bS)-5-Hydroxy-6b-(hydroxyacetyl)-4a,6a,8,8-tetramethyl-4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-2H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-2-on |
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(4aR,4bS,5S,6aS,6bS,9aR,10aS,10bS)-6b-Glycoloyl-5-hydroxy-4a,6a,8,8-tetramethyl-4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-2H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-2-one |
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11b,21-Dihydroxy-16a,17-isopropylidenedioxy-1,4-pregnadiene-3,20-dione |
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Topifug |
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d-2083 |
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EINECS 211-351-6 |
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11,21-Dihydroxy-16,17-[(1-methylethylidene)bis(oxy)]pregna-1,4-diene-3,20-dione |
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Budesonide Impurity 6 |
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