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培氟沙星
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| 中文名 |
培氟沙星 |
|---|---|
| 英文名 |
Pefloxacin mesylate dihydrate |
| 中文别名 |
盐酸地布卡因 | 1-乙基-6-氟-7-(4-甲基哌嗪-1-基)-4-氧代喹啉-3-羧酸 | 1-乙基-6-氟-7-(4-甲基哌嗪基)-4-氧代-1,4-二氢喹啉-3-羧酸甲磺酸盐 |
| 英文别名 |
更多 |
| 描述 |
去水甲磺酸Pefloxacin是抗菌素，能通过抑制DNA旋转酶阻断细菌DNA复制。 |
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| 相关类别 |
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| 溶解度 |
体外：
在DMSO中10mM
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| 储备液 |
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| 存储 |
请将产品存放在分析证书中的建议条件下。
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| 运输 |
室温;可能会有所不同 |
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| SMILES |
O=C(C1=CN(CC)C2=C(C=C(F)C(N3CCN(C)CC3)=C2)C1=O)O.CS(=O)(O)=O.O.O |
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| 参考文献 |
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| 相关活性 小分子 |
嘌呤霉素盐酸盐 | G-418 硫酸盐 | 衣霉素 | 潮霉素B | 盐霉素 | 阿维巴坦钠 | 硫酸新霉素 | 法硼巴坦 | 甲氧西林钠 | 利福平 | 甲硝唑 | 羧苄青霉素钠 | 头孢他啶 | Eravacycline dihydrochloride | 头孢噻肟钠 |
| 沸点 | 529.1?C at 760mmHg |
|---|---|
| 熔点 | 271?C |
| 分子式 | C18H28FN3O8S |
| 分子量 | 465.49400 |
| 闪点 | 273.8?C |
| 精确质量 | 465.15800 |
| PSA | 146.99000 |
| LogP | 2.06960 |
| 储存条件 | Store at?0-5°C |
| 符号 |
GHS07 |
|---|---|
| 信号词 |
Warning |
| 危害声明 |
H319 |
| 警示性声明 |
P305 + P351 + P338 |
| 个人防护装备 |
dust mask type N95 (US);Eyeshields;Gloves |
| 危害码 (欧洲) |
Xn |
| 风险声明 (欧洲) |
22-36 |
| 安全声明 (欧洲) |
26 |
| 危险品运输编码 | NONH for all modes of transport |
| RTECS号 | VB2002200 |
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Pefloxacin-induced achilles tendon toxicity in rodents: biochemical changes in proteoglycan synthesis and oxidative damage to collagen. Antimicrob. Agents Chemother. 44 , 867-872, (2000)
Despite a relatively low incidence of serious side effects, fluoroquinolones and the fluoroquinolone pefloxacin have been reported to occasionally promote tendinopathy that might result in the complic…
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Cytotoxicity and uptake of pefloxacin, ciprofloxacin, and ofloxacin in primary cultures of rat hepatocytes. J. Antimicrob. Chemother. 24 , 355-363, (1989)
The cytotoxicity and the uptake of three 4-quinolones–pefloxacin, ciprofloxacin, and ofloxacin–were investigated in primary cultures of rat hepatocytes. As assessed by intracellular enzyme release i…
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MFCD01685696 |
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1-ethyl-6-fluoro-7-(4-methylpiperazin-1-yl)-4-oxoquinoline-3-carboxylic acid,methanesulfonic acid,dihydrate |
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EINECS 274-613-9 |
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Pefloxacin mesilate dihydrate |
|
3-Quinolinecarboxylic acid (1-ethyl-6-fluoro-1,4-dihydro-7-(4-methyl-1-piperazinyl)-4-oxo |
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