中文名 |
头孢美唑钠 |
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英文名 |
cefmetazole sodium |
中文别名 |
(6R,7S)-7-[[2-(氰甲基硫)乙酰]氨基]-7-甲氧基-3-[(1-甲基四唑-5-基)硫甲基]-8-氧代-5-硫杂-1-氮杂双环[4.2.0]辛-2-烯-2-甲酸钠盐 |
英文别名 |
更多 |
描述 |
Cefmetazole钠是一种半合成的广谱头孢菌素类抗菌剂。 |
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相关类别 |
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溶解度 |
体外:
DMSO:≥39mg / mL(79.02 mM) * “≥”表示可溶,但饱和度未知。
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储备液 |
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存储 |
4°C,避光
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运输 |
室温;可能会有所不同 |
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SMILES |
O=C(C(N12)=C(CSC3=NN=NN3C)CS[C@]2([H])[C@](OC)(NC(CSCC#N)=O)C1=O)[O-].[Na+] |
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参考文献 |
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相关活性 小分子 |
嘌呤霉素盐酸盐 | G-418 硫酸盐 | 衣霉素 | 潮霉素B | 盐霉素 | 阿维巴坦钠 | 硫酸新霉素 | 法硼巴坦 | 甲氧西林钠 | 利福平 | 甲硝唑 | 羧苄青霉素钠 | 头孢他啶 | Eravacycline dihydrochloride | 头孢噻肟钠 |
密度 | 1.75 g/cm3 |
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分子式 | C15H16N7NaO5S3 |
分子量 | 493.516 |
精确质量 | 493.027283 |
PSA | 242.06000 |
外观性状 | 白色固体 |
储存条件 | 库房低温通风干燥 |
水溶解性 | 水溶性:完全溶解;易溶于:甲醇;可溶于:丙酮;极微溶:乙醇;不溶:氯仿,四氢呋喃 |
头孢美唑钠毒性英文版
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符号 |
GHS07, GHS08 |
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信号词 |
Danger |
危害声明 |
H315-H317-H319-H334-H335 |
警示性声明 |
P261-P280-P305 + P351 + P338-P342 + P311 |
危害码 (欧洲) |
Xi:Irritant; |
风险声明 (欧洲) |
R36/37/38;R42/43 |
安全声明 (欧洲) |
S26-S36 |
危险品运输编码 | NONH for all modes of transport |
WGK德国 | 2 |
RTECS号 | XI0372200 |
Chimeric mice with humanized liver. Toxicology 246(1) , 9-17, (2008)
Recently, chimeric mice with humanized liver were established by transplanting human hepatocytes into an urokinase-type plasminogen activator(+/+)/severe combined immunodeficient transgenic mouse line…
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Usefulness of sennoside as an agent for mechanical bowel preparation prior to elective colon cancer surgery Asian J. Surg. 35(2) , 81-7, (2012)
Objective We retrospectively evaluated the usefulness of sennoside as an agent for mechanical bowel preparation prior to elective colon cancer surgery.
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Involvement of multidrug resistance-associated protein 4 in efflux transport of prostaglandin E(2) across mouse blood-brain barrier and its inhibition by intravenous administration of cephalosporins. J. Pharmacol. Exp. Ther. 333 , 912-919, (2010)
Prostaglandin E(2) (PGE(2)) acts as a modulator of synaptic signaling and excitability in the brain. Because PGE(2) is barely inactivated enzymatically in adult brain, its brain level is considered to…
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5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[2-[(cyanomethyl)thio]acetyl]amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-, sodium salt, (6R,7S)- (1:1) |
sodium,(6R,7S)-7-[[2-(cyanomethylsulfanyl)acetyl]amino]-7-methoxy-3-[(1-methyltetrazol-5-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate |
Sodium (6R,7S)-7-(2-((Cyanomethyl)thio)acetamido)-7-methoxy-3-(((1-methyl-1H-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate |
MFCD00865068 |
Cefmetazole Sodium Salt |
Sodium (6R,7S)-7-({[(cyanomethyl)sulfanyl]acetyl}amino)-7-methoxy-3-{[(1-methyl-1H-tetrazol-5-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate |
Cefmetazole (sodium) |