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奥比沙星
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| 中文名 |
奥比沙星 |
|---|---|
| 英文名 |
Orbifloxacin |
| 中文别名 |
1-环丙基-5,6,8-三氟-7-(CIS-3,5-二甲基哌嗪)-1,4-二氢-4-氧-喹啉-3-羧酸 | 三氯苯咪唑 | 1-环丙基-5,6,8-三氟-7-(Cis-3,5-二甲基哌嗪)-1,4-二氢-4-氧-喹啉-3-羧酸 | 1-环丙基-5,6,8-三氟-7-(顺式-3,5-二甲基哌嗪)-1,4-二氢-4-氧代喹啉-3-羧酸 |
| 英文别名 |
更多 |
| 描述 |
Orbifloxacin是一种合成的氟喹诺酮类广谱抗生素，已被批准用于犬类。 |
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| 相关类别 |
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| 溶解度 |
体外：
DMSO：6 mg / mL（15.18 mM;需要超声波和加热）
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| 储备液 |
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| 存储 |
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| 运输 |
室温;可能会有所不同 |
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| SMILES |
O=C(C1=CN(C2CC2)C3=C(C(F)=C(F)C(N4C[C@H](C)N[C@H](C)C4)=C3F)C1=O)O |
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| 相关活性 小分子 |
嘌呤霉素盐酸盐 | G-418 硫酸盐 | 衣霉素 | 潮霉素B | 盐霉素 | 阿维巴坦钠 | 硫酸新霉素 | 法硼巴坦 | 甲氧西林钠 | 利福平 | 甲硝唑 | 羧苄青霉素钠 | 头孢他啶 | Eravacycline dihydrochloride | 头孢噻肟钠 |
| 密度 | 1.4±0.1 g/cm3 |
|---|---|
| 沸点 | 590.7±50.0 °C at 760 mmHg |
| 熔点 | 260 °C(dec.) |
| 分子式 | C19H20F3N3O3 |
| 分子量 | 395.376 |
| 闪点 | 311.1±30.1 °C |
| 精确质量 | 395.145691 |
| PSA | 74.57000 |
| LogP | 2.37 |
| 外观性状 | 固体;White to Orange to Green powder to crystal |
| 蒸汽压 | 0.0±1.7 mmHg at 25°C |
| 折射率 | 1.588 |
| 个人防护装备 |
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| 危险品运输编码 | NONH for all modes of transport |
|
~72%
奥比沙星
113617-63-3
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文献：Miyamoto, Teruyuki; Matsumoto, Jun-ichi; Chiba, Katsumi; Egawa, Hiroshi; Shibamori, Koh-ichiro; et al. Journal of Medicinal Chemistry, 1990 , vol. 33, # 6 p. 1645 – 1656 |
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Simultaneous determination of 38 veterinary antibiotic residues in raw milk by UPLC-MS/MS. Food Chem. 181 , 119-26, (2015)
A selective and rapid method has been developed to determine, simultaneously, 38 veterinary antibiotic residues in raw milk by ultra-high-performance liquid chromatography-tandem mass spectrometry (UP…
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Multi-residue Determination of Polar Veterinary Drugs in Livestock and Fishery Products by Liquid Chromatography/Tandem Mass Spectrometry. J. AOAC Int. 98(1) , 230-47, (2015)
Residues of 37 polar veterinary drugs belonging to six families (quinolones, tetracyclines, macrolides, lincosamides, sulfonamides, and others) in livestock and fishery products were determined using …
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Development of a novel genetically modified bioluminescent-bacteria-based assay for detection of fluoroquinolones in animal-derived foods. Anal. Bioanal. Chem 406(30) , 7899-910, (2014)
Fluoroquinolones (FQNs) are broad-spectrum antibacterial agents widely used in animal husbandry and aquaculture. The residues and antimicrobial resistance of such antibiotics are a major public health…
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1-cyclopropyl-7-[(3r,5s)-3,5-dimethylpiperazin-1-yl]-5,6,8-trifluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid |
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Orbifloxacin |
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3-Quinolinecarboxylic acid, 1-cyclopropyl-7-[(3R,5S)-3,5-dimethyl-1-piperazinyl]-5,6,8-trifluoro-1,4-dihydro-4-oxo- |
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1-cyclopropyl-7-[(3S,5R)-3,5-dimethylpiperazin-1-yl]-5,6,8-trifluoro-4-oxoquinoline-3-carboxylic acid |
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Orbax |
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1-Cyclopropyl-7-[(3R,5S)-3,5-dimethyl-1-piperazinyl]-5,6,8-trifluoro-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid |
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MFCD00864858 |
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