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帕马溴
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| 中文名 |
帕马溴 |
|---|---|
| 英文名 |
2-amino-2-methylpropan-1-ol,8-bromo-1,3-dimethyl-7H-purine-2,6-dione |
| 中文别名 |
2-氨基-2-甲基丙醇 8-溴胆茶碱 |
| 英文别名 |
更多 |
| 描述 |
Pamabron是利尿剂，可缓解月经相关症状，其有效成分为8-bromotheophylline。 |
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| 相关类别 |
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| 溶解度 |
体外：
DMSO：150 mg / mL（430.79 mM;需要超声波） 体内：1。逐个添加每种溶剂：10％DMSO 90％（20％SBE-β-CD在盐水中）溶解度：≥2.67mg / mL（7.67 mM）;澄清溶液2.逐个添加每种溶剂：10％DMSO 90％玉米油溶解度：≥2.67mg / mL（7.67 mM）;澄清溶液3.逐个添加每种溶剂：10％DMSO 40％PEG300 5％吐温-80 45％盐水溶解度：≥2.67mg/ mL（7.67mM）;明确解决方案
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| 储备液 |
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| 存储 |
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| 运输 |
室温;可能会有所不同 |
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| SMILES |
O=C(N1C)N(C)C2=C(N=C(Br)N2)C1=O.CC(C)(N)CO |
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| 参考文献 |
[4]. Pamabrom
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| 相关活性 小分子 |
磺丁醚-beta-环糊精 | 环孢菌素 | 2,7-二氯二氢代荧光黄二醋酸 | 1-甲基-4-苯基-1,2,3,6-四氢吡啶盐酸盐 | 4′,4”-双-2-咪唑啉-2-基对苯二丙烯酰苯胺二盐酸盐 | 乙莫克舍 | TD139 | Mitoquinone甲磺酸盐 | GSK2795039 | 5,5’,6,6’-四氯-1,1’,3,3’-四乙基苯并咪唑羰花青碘化物 | 胞内钙荧光探针 BAPTA-AM | AP20187 | GKT137831 | D-虫荧光素游离酸 | 野百合碱 |
| 沸点 | 469.5?C at 760 mmHg |
|---|---|
| 熔点 | >300?C |
| 分子式 | C11H18BrN5O3 |
| 分子量 | 348.19600 |
| 闪点 | 237.7?C |
| 精确质量 | 347.05900 |
| PSA | 118.93000 |
| LogP | 0.13910 |
| 储存条件 | Refrigerator |
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Serum sickness-like reaction to Pamabrom. Journal. of. Drugs in. Dermatology. 5(3) , 284-6, (2006)
Pamabron is a common over-the-counter diuretic used for relief of menstrual-associated symptoms. An urticarial eruption, with systemic complaints consistent with a serum sickness-like reaction, attrib…
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Fixed drug eruption from pamabrom. Cleve. Clin. J. Med. 58(1) , 33-4, (1991)
A young woman presented with recurrent skin lesions that were predominantly perioral. Fixed drug reaction was diagnosed based on her history of intermittent ingestion of Pamprin, a common menstrual sy…
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Primary dysmenorrhea among Mexican university students: prevalence, impact and treatment. Eur. J. Obstet. Gynecol. Reprod. Biol. 152(1) , 73-7, (2010)
To evaluate the prevalence, impact and treatment of primary dysmenorrhea among Mexican university students.A multiple-choice questionnaire was administered to 1539 students in six university programs:…
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Predema |
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2-amino-2-methylpropanol 8-bromotheophyllinate |
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Premsyn PMS |
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EINECS 210-103-4 |
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Pamabrom| |
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MFCD00867328 |
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8-bromo-3,7-dihydro-1,3-dimethyl-1H-purine-2,6-dione |
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8-Brom-1,3-dimethyl-3,7-dihydro-purin-2,6-dion,Verbindung mit 2-Amino-2-methyl-propan-1-ol |
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8-bromo-1,3-dimethyl-3,7-dihydro-purine-2,6-dione,compound with 2-amino-2-methyl-propan-1-ol |
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UNII-UA8U0KJM72 |
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Sunril |
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Pamabrom |
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