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扁蓄苷

扁蓄苷

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?扁蓄苷名称


















中文名

扁蓄苷
英文名

avicularin
中文别名


蓄苷




|



蓄苷



英文别名
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?扁蓄苷生物活性


































描述
Avicularin 是一种存在多种植物中有生物活性的黄酮类化合物，具有抗炎、抗过敏、抗氧化、保肝、抗肿瘤等作用。在 LPS 刺激的 RAW 264.7 巨噬细胞中，Avicularin 通过抑制 ERK 信号通路产生抗炎活性。Avicularin 能通过调节 NF-κB(p65)、COX-2 和 PPAR-γ 的活性来改善人类肝细胞癌。
相关类别




SMILES

O=C1C(O[C@H]2[C@@H]([C@H]([C@H](CO)O2)O)O)=C(C3=CC=C(O)C(O)=C3)OC4=CC(O)=CC(O)=C14
参考文献

[1]. Vo VA, et al. Avicularin Inhibits Lipopolysaccharide-Induced Inflammatory Response by Suppressing ERK Phosphorylation in RAW 264.7 Macrophages. Biomol Ther (Seoul). 2012 Nov;20(6):532-7.

[2]. Wang Z, et al. Avicularin ameliorates human hepatocellular carcinoma via the regulation of NF?κB/COX?2/PPAR?γ activities. Mol Med Rep. 2019 Jun;19(6):5417-5423.






?扁蓄苷物理化学性质









































密度 1.9±0.1 g/cm3
沸点 855.4±65.0 °C at 760 mmHg
熔点 240-243?C
分子式 C20H18O11
分子量 434.350
闪点 305.8±27.8 °C
精确质量 434.084900
PSA 190.28000
LogP 2.06
外观性状 白色粉末
蒸汽压 0.0±0.3 mmHg at 25°C
折射率 1.802






?扁蓄苷安全信息
















危险品运输编码 NONH for all modes of transport






?扁蓄苷上下游产品











扁蓄苷上游产品? 0

扁蓄苷下游产品? 3













?扁蓄苷文献12

更多文献














Protective effect of components isolated from Lindera erythrocarpa against oxidative stress-induced apoptosis of H9c2 cardiomyocytes.

Phytother Res. 25(11) , 1612-7, (2011)

Eight compounds were isolated from the methanol fraction of Lindera erythrocarpa and assessed for their ability to protect H9c2 cardiomyocytes against oxidative stress-induced cell death. Three of the…



Inhibitory activity against urease of quercetin glycosides isolated from Allium cepa and Psidium guajava.

Biosci. Biotechnol. Biochem. 74 , 878-880, (2010)

Methanolic extracts of edible plants and seaweeds were tested for their inhibitory activity against Jack bean urease. Quercetin-4′-O-beta-D-glucopyranoside was isolated from Allium cepa as a urease in…



[Determination of avicularin in Polygonum aviculare L].

Yao Xue Xue Bao 18(9) , 700-4, (1983)







?扁蓄苷英文别名




































4H-1-Benzopyran-4-one, 3-(α-L-arabinofuranosyloxy)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-


Fenicularin


2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-4-oxo-4H-chromen-3-yl α-L-arabinofuranoside


Quercetin 3-α-L-arabinofuranoside


Avicularin


QUERCETIN-3-ARABINOSIDE


Avicularoside


Avicularine


Avicularin,Quercetin 3-alpha-L-arabinofuranoside








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