密度 | 1.5±0.1 g/cm3 |
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沸点 | 751.6±60.0 °C at 760 mmHg |
分子式 | C29H25BrN2O5 |
分子量 | 561.423 |
闪点 | 408.4±32.9 °C |
精确质量 | 560.094666 |
LogP | 4.55 |
蒸汽压 | 0.0±2.5 mmHg at 25°C |
折射率 | 1.669 |
储存条件 |
2-8°C密闭、阴凉干燥处 |
稳定性 |
Analysis Note The enzyme must be activated for 2-3 hours before use by dissolving in 2.5 mM dithiothreitol containing 1.0 mM calcium acetate. Quality Purified, essentially salt-free Unit Definition One unit will hydrolyze 1.0 μmole of BAEE per min at pH 7.6 at 25 °C in the presence of 2.5 mM DTT. |
计算化学 |
计算化学数据: 1、 疏水参数计算参考值(XlogP):4.6 2、 氢键供体数量:1 3、 氢键受体数量:2 4、 可旋转化学键数量:6 5、 拓扑分子极性表面积(TPSA):37.3 6、 重原子数量:17 7、 表面电荷:0 8、 复杂度:234 9、 同位素原子数量:0 10、 确定原子立构中心数量:0 11、 不确定原子立构中心数量:1 12、 确定化学键立构中心数量:0 13、 不确定化学键立构中心数量:0 14、 共价键单元数量:1 |
更多 |
1. 性状:冻干粉末。 2. 密度(g/mL,25℃):未确定 3. 相对蒸汽密度(g/mL,空气=1):未确定 4. 熔点(?C):未确定 5. 沸点(?C,常压):未确定 6. 沸点(?C,5.2kPa):未确定 7. 折射率:未确定 8. 闪点(?C):未确定 9. 比旋光度(?):未确定 10. 自燃点或引燃温度(?C):未确定 11. 蒸气压(kPa,20?C):未确定 12. 饱和蒸气压(kPa,60?C):未确定 13. 燃烧热(KJ/mol):未确定 14. 临界温度(?C):未确定 15. 临界压力(KPa):未确定 16. 油水(辛醇/水)分配系数的对数值:未确定 17. 爆炸上限(%,V/V):未确定 18. 爆炸下限(%,V/V):未确定 19. 溶解性:溶于水 |
梭菌蛋白酶毒性英文版
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个人防护装备 |
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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危险品运输编码 | NONH for all modes of transport |
从溶组织梭状芽孢杆菌(Clostridium histolyticum)中分离而得的肽链内切酶。
Determination of the cytotoxic effect of Clostridium histolyticum culture supernatant on HeLa cells in the presence of protease inhibitors. FEMS Immunol. Med. Microbiol. 45(2) , 137-42, (2005)
Clostridium histolyticum culture supernatant contains numerous enzymes, which exert a cytotoxic effect on host cells. This includes lethal toxin, clostripain and high-potassium-sensitive toxin. Since …
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High-level production and purification of clostripain expressed in a virulence-attenuated strain of Clostridium perfringens. Protein Expr. Purif. 76(1) , 83-9, (2011)
Clostripain (CLO) produced by Clostridium histolyticum is an arginine-specific endopeptidase with the potential for applicability to diverse medical and industrial uses. In this study, we developed an…
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Protease-mediated ligation of abiotic oligomers. J. Am. Chem. Soc. 127(49) , 17132-3, (2005)
We demonstrate that proteases can catalyze the ligation of peptidomimetic oligomers. The enzyme clostripain was used to facilitate the native ligation of N-substituted glycine oligomers, or peptoids. …
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MFCD00130814 |
Pyrrolo[3,4-c]carbazole-1,3(2H,3aH)-dione, 9-bromo-4,5,6,10c-tetrahydro-2-phenyl-4-(3,4,5-trimethoxyphenyl)- |
9-Bromo-2-phenyl-4-(3,4,5-trimethoxyphenyl)-4,5,6,10c-tetrahydropyrrolo[3,4-c]carbazole-1,3(2H,3aH)-dione |