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氯帕胺
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| 描述 |
Clopamide 是一种具有口服活性的噻嗪类利尿剂，可抑制钠耦合的氯离子共转运蛋白 SLC12A3。Clopamide 可用于高血压和心力衰竭的研究。 |
|---|---|
| 相关类别 |
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| 体外研究 |
氯丙胺由肾小管细胞主动分泌，真正的肾小管排泄分数（TTEF）值为10%[3]。 |
| 体内研究 |
清醒犬口服氯丙胺（0.5 mg/kg）和同时局部输注环孢素-A（1-10μg/min）后，缓激肽的静脉收缩反应减弱[4]。 |
| 存储 |
请将产品存放在分析证书中的建议条件下。
|
| 运输 |
室温 |
| SMILES |
O=C(NN1[C@H](C)CCC[C@@H]1C)C2=CC=C(Cl)C(S(=O)(N)=O)=C2 |
| 参考文献 |
|
| 密度 | 1.4±0.1 g/cm3 |
|---|---|
| 熔点 | 244-246?C |
| 分子式 | C14H20ClN3O3S |
| 分子量 | 345.845 |
| 精确质量 | 345.091400 |
| PSA | 100.88000 |
| LogP | 1.59 |
| 外观性状 | 白色至淡黄色结晶粉末 |
| 折射率 | 1.613 |
| 储存条件 | 2-8°C |
| 符号 |
GHS08 |
|---|---|
| 信号词 |
Danger |
| 危害声明 |
H317-H334 |
| 警示性声明 |
P261-P280-P284-P304 + P340-P342 + P311 |
| 危害码 (欧洲) |
Xn |
| 风险声明 (欧洲) |
R42/43 |
| 安全声明 (欧洲) |
36 |
| 危险品运输编码 | NONH for all modes of transport |
| WGK德国 | 3 |
| 海关编码 | 2935009090 |
| 海关编码 | 2935009090 |
|---|---|
| 中文概述 | 2935009090 其他磺（酰）胺. 增值税率:17.0% 退税率:9.0% 监管条件:无 最惠国关税:6.5% 普通关税:35.0% |
| 申报要素 | 品名, 成分含量, 用途 |
| Summary | 2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0% |
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Ultra high performance supercritical fluid chromatography coupled with tandem mass spectrometry for screening of doping agents. I: Investigation of mobile phase and MS conditions. Anal. Chim. Acta 853 , 637-46, (2014)
The conditions for the analysis of selected doping substances by UHPSFC-MS/MS were optimized to ensure suitable peak shapes and maximized MS responses. A representative mixture of 31 acidic and basic …
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Ultra high performance supercritical fluid chromatography coupled with tandem mass spectrometry for screening of doping agents. II: Analysis of biological samples. Anal. Chim. Acta 853 , 647-59, (2014)
The potential and applicability of UHPSFC-MS/MS for anti-doping screening in urine samples were tested for the first time. For this purpose, a group of 110 doping agents with diverse physicochemical p…
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Effects of pindolol, or a pindolol/clopamide combination preparation, on plasma lipid levels in essential hypertension. Hunter Hypertension Research Group. Med. J. Aust. 150(11) , 646, 648, 651-2, (1989)
In an open study that was conducted in general practice, 22 patients with previously-untreated mild hypertension received an average daily dose of 11.7 mg of pindolol over a 50-week study period. The …
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EINECS 211-261-7 |
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Brinaldix |
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DT-327 |
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4-Chloro-N-[(2R,6S)-2,6-dimethyl-1-piperidinyl]-3-sulfamoylbenzamide |
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Benzamide, 3-(aminosulfonyl)-4-chloro-N-(2,6-dimethyl-1-piperidinyl)-, cis- |
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CLOPAMIDUM |
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ChlosudiMepriMyl |
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Adurix |
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MFCD00941495 |
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4-Chloro-N-(2,6-dimethylpiperidino)-3-sulfamoylbenzamide |
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3-(aminosulfonyl)-4-chloro-N-(2,6-dimethylpiperidin-1-yl)benzamide |
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Aquex |
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4-Chloro-N-(2,6-dimethylpiperidin-1-yl)-3-sulfamoylbenzamide |
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Benzamide, 3-(aminosulfonyl)-4-chloro-N-[(2R,6S)-2,6-dimethyl-1-piperidinyl]- |
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Benzamide, 3-(aminosulfonyl)-4-chloro-N-(2,6-dimethyl-1-piperidinyl)- |
|
4-Chloro-N-(2,6-dimethyl-1-piperidinyl)-3-sulfamoylbenzamide |
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