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水飞蓟亭
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客户评价
| 描述 |
Silychristin 是水飞蓟果实中富含的黄酮类化合物，具有抗氧化作用。Silychristin 是甲状腺激素转运体 MCT8 的有效抑制剂，能强烈抑制 T3 的摄取，其 IC50 为 110 nM。 |
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| 相关类别 |
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| SMILES |
O=C1[C@H](O)[C@@H](C2=CC(O)=C(O[C@@H](C3=CC=C(O)C(OC)=C3)[C@@H]4CO)C4=C2)OC5=CC(O)=CC(O)=C15 |
| 参考文献 |
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| 密度 | 1.6±0.1 g/cm3 |
|---|---|
| 沸点 | 782.0±60.0 °C at 760 mmHg |
| 分子式 | C25H22O10 |
| 分子量 | 482.436 |
| 闪点 | 270.5±26.4 °C |
| 精确质量 | 482.121307 |
| PSA | 166.14000 |
| LogP | 2.20 |
| 蒸汽压 | 0.0±2.8 mmHg at 25°C |
| 折射率 | 1.716 |
| 储存条件 | 2-8°C |
| 符号 |
GHS07 |
|---|---|
| 信号词 |
Warning |
| 危害声明 |
H302 |
| 危害码 (欧洲) |
Xn |
| 风险声明 (欧洲) |
22 |
| 安全声明 (欧洲) |
22-45 |
| 危险品运输编码 | NONH for all modes of transport |
| 水飞蓟亭上游产品? 3 | |
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| 水飞蓟亭下游产品? 0 | |
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Effect of the flavanolignans of Silybum marianum L. on lipid peroxidation in rat liver microsomes and freshly isolated hepatocytes. Pharmacol. Res. 25(2) , 147-54, (1992)
The effect of several flavanolignans (silicristin, silidianin, silybin and isosilybin) present in silymarin, the extract of Silybum marianum fruits, was tested on lipid peroxidation in rat liver micro…
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Separation and characterization of silybin, isosilybin, silydianin and silychristin in milk thistle extract by liquid chromatography-electrospray tandem mass spectrometry. J. Chromatogr. A. 1116(1-2) , 57-68, (2006)
A selective and sensitive liquid chromatography/tandem mass spectrometry (LC/MS/MS) method has been developed for the characterization of silymarin in commercially available milk thistle extract. In t…
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Identifying the differential effects of silymarin constituents on cell growth and cell cycle regulatory molecules in human prostate cancer cells. Int. J. Cancer 123(1) , 41-50, (2008)
Prostate cancer (PCa) is the leading cause of cancer-related deaths in men; urgent measures are warranted to lower this deadly malignancy. Silymarin is a known cancer chemopreventive agent, but the re…
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Silicristin |
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EINECS 251-720-9 |
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Silicristinum |
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(2R,3R)-3,5,7-trihydroxy-2-[(2R,3S)-7-hydroxy-2-(4-hydroxy-3-methoxyphenyl)-3-(hydroxymethyl)-2,3-dihydro-1-benzofuran-5-yl]-2,3-dihydrochromen-4-one |
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Silicristinum [INN-Latin] |
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Silicristina |
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(2R,3R)-3,5,7-Trihydroxy-2-[(2R,3S)-7-hydroxy-2-(4-hydroxy-3-methoxyphenyl)-3-(hydroxymethyl)-2,3-dihydro-1-benzofuran-5-yl]-2,3-dihydro-4H-chromen-4-one |
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Silicristina [INN-Spanish] |
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4H-1-Benzopyran-4-one, 2-[(2R,3S)-2,3-dihydro-7-hydroxy-2-(4-hydroxy-3-methoxyphenyl)-3-(hydroxymethyl)-5-benzofuranyl]-2,3-dihydro-3,5,7-trihydroxy-, (2R,3R)- |
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Silychristin |
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Silymarin II |
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Silicristine [INN-French] |
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(2R,3R)-3,5,7-trihydroxy-2-[(2R,3S)-7-hydroxy-2-(4-hydroxy-3-methoxyphenyl)-3-hydroxymethyl-2,3-dihydrobenzofuran-5-yl]chroman-4-one |
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Silicristine |
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