洛贝林

Product NameL-LOBELINE FREE BASE

Product NumberL7149

Company

Century Ba-Shi Building 22A-B,

200020 Shanghai

Technical Phone #86-21-61415566

Fax 86-21-61415567

E-mail Address

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2 – Hazards Identification

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SPECIAL INDICATION OF HAZARDS TO HUMANS AND THE ENVIRONMENT

Toxic by inhalation, in contact with skin and if swallowed.

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3 – Composition/Information on Ingredients

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Product NameCAS #EC noAnnex I

Index Number

L-LOBELINE FREE BASE90-69-7202-012-3 None

FormulaC22H27NO2

Molecular Weight 337,5000 AMU

Synonyms8,10-Diphenyllobelionol *

2-(6-(beta-Hydroxy-phenethyl)-1-methyl-2-piperidy

l)acetophenone *

2-(6-(2-Hydroxy-2-phenylethyl)-1-methyl-2-piperid

inyl)-1-phenylethanone * Inflatine * Lobelin *

(-)-Lobeline * alpha-Lobeline * Lobnico

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4 – First Aid Measures

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AFTER INHALATION

If inhaled, remove to fresh air. If breathing becomes difficult,

call a physician.

AFTER SKIN CONTACT

In case of skin contact, flush with copious amounts of water for

at least 15 minutes. Remove contaminated clothing and shoes.

Call a physician.

AFTER EYE CONTACT

In case of contact with eyes, flush with copious amounts of

water for at least 15 minutes. Assure adequate flushing by

separating the eyelids with fingers. Call a physician.

AFTER INGESTION

If swallowed, wash out mouth with water provided person is

conscious. Call a physician.

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5 – Fire Fighting Measures

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EXTINGUISHING MEDIA

Suitable: Carbon dioxide, dry chemical powder, or appropriate

foam.

SPECIAL PROTECTIVE EQUIPMENT FOR FIREFIGHTERS

Wear self-contained breathing apparatus and protective clothing

to prevent contact with skin and eyes.

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6 – Accidental Release Measures

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PROCEDURE(S) OF PERSONAL PRECAUTION(S)

Wear respirator, chemical safety goggles, rubber boots, and

heavy rubber gloves.

METHODS FOR CLEANING UP

Sweep up, place in a bag and hold for waste disposal. Avoid

raising dust. Ventilate area and wash spill site after material

pickup is complete.

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7 – Handling and Storage

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8 – Exposure Controls / Personal Protection

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ENGINEERING CONTROLS

Mechanical exhaust.

PERSONAL PROTECTIVE EQUIPMENT

Respiratory Protection: Use respirators and components tested and

approved under appropriate government standards such as NIOSH (US)

or CEN (EU). Where risk assessment shows air-purifying respirators

are appropriate use a full-face particle respirator type N99 (US)

or type P2 (EN 143) respirator cartridges as a backup to

engineering controls. If the respirator is the sole means of

protection, use a full-face supplied air respirator.

Hand Protection: Compatible chemical-resistant gloves.

Eye Protection: Chemical safety goggles.

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9 – Physical and Chemical Properties

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AppearancePhysical State: Solid

PropertyValueAt Temperature or Pressure

pHN/A

BP/BP RangeN/A

MP/MP RangeN/A

Flash PointN/A

FlammabilityN/A

Autoignition TempN/A

Oxidizing PropertiesN/A

Explosive PropertiesN/A

Explosion LimitsN/A

Vapor PressureN/A

Partition CoefficientN/A

ViscosityN/A

Vapor DensityN/A

Saturated Vapor Conc. N/A

Evaporation RateN/A

Bulk DensityN/A

Decomposition Temp.N/A

Solvent ContentN/A

Water ContentN/A

Surface TensionN/A

ConductivityN/A

Miscellaneous DataN/A

SolubilityN/A

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10 – Stability and Reactivity

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STABILITY

Stable: Stable.

HAZARDOUS DECOMPOSITION PRODUCTS

Hazardous Decomposition Products: Carbon monoxide, Carbon dioxide,

Nitrogen oxides.

HAZARDOUS POLYMERIZATION

Hazardous Polymerization: Will not occur

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11 – Toxicological Information

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RTECS NUMBER: OJ8480000

ACUTE TOXICITY

LD50

Intraperitoneal

Mouse

43500 UG/KG

LD50

Intravenous

Mouse

6300 UG/KG

LD50

Subcutaneous

Rabbit

35 MG/KG

SIGNS AND SYMPTOMS OF EXPOSURE

Stomach pains, vomiting, diarrhea. Exposure can cause:

ROUTE OF EXPOSURE

Multiple Routes: Harmful if swallowed, inhaled, or absorbed

through skin. May cause irritation.

TARGET ORGAN INFORMATION

Central nervous system. Peripheral nervous system.

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12 – Ecological Information

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No data available.

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13 – Disposal Considerations

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SUBSTANCE DISPOSAL

Dissolve or mix the material with a combustible solvent and burn

in a chemical incinerator equipped with an afterburner and

scrubber. Observe all federal, state, and local environmental

regulations.

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14 – Transport Information

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RID/ADR

UN#: 1544

Class: 6.1

PG: III

Proper Shipping Name: Alkaloids, solid, n.o.s.

IMDG

UN#: 1544

Class: 6.1

PG: III

Proper Shipping Name: Alkaloids, solid, n.o.s.

Marine Pollutant: No

Severe Marine Pollutant: No

Technical Name: Required

IATA

UN#: 1544

Class: 6.1

PG: III

Proper Shipping Name: Alkaloids, solid, n.o.s.

Inhalation Packing Group I: No

Technical Name: Required

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15 – Regulatory Information

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CLASSIFICATION AND LABELING ACCORDING TO EU DIRECTIVES

INDICATION OF DANGER: T

Toxic.

R-PHRASES: 23/24/25

Toxic by inhalation, in contact with skin and if swallowed.

S-PHRASES: 36/37/39-45

Wear suitable protective clothing, gloves, and eye/face

protection. In case of accident or if you feel unwell, seek

medical advice immediately (show the label where possible).

COUNTRY SPECIFIC INFORMATION

Germany

WGK: 3

Self-Classification

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16 – Other Information

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WARRANTY

The above information is believed to be correct but does not

purport to be all inclusive and shall be used only as a guide. The

information in this document is based on the present state of our

knowledge and is applicable to the product with regard to

appropriate safety precautions. It does not represent any

shall not be held liable for any damage resulting from handling or

from contact with the above product. See reverse side of invoice

or packing slip for additional terms and conditions of sale.

unlimitedpaper copies for internal use only.

DISCLAIMER

For R&D use only. Not for drug, household or other uses.

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模块 15 – 法规信息

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模块16 – 其他信息

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