灰叶草素, 羟基鱼藤素

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中文名	灰叶草素, 羟基鱼藤素
英文名	tephrosin
英文别名	更多

描述	Tephrosin 是一种天然类胡萝卜素，具有较强的抗肿瘤活性。Tephrosin 通过诱导受体内化来诱导 EGFR 和 ErbB2 的降解。
相关类别	研究领域 >> 癌症信号通路 >> 其他 >> 其他
体外研究	用tephrosin（0-10μM）处理HT-29细胞抑制EGFR，ErbB2和ErbB3的配体诱导和组成型磷酸化，并同时抑制下游信号分子如Akt和Erk1/2丝裂原活化蛋白激酶的活化。（MAPK）[1]。
存储	请将产品存放在分析证书中的建议条件下。
运输	室温
SMILES	O=C1[C@]2(O)[C@](COC3=CC(OC)=C(OC)C=C32)([H])OC4=C5C=CC(C)(C)OC5=CC=C14
参考文献	[1]. Choi S, et al. Tephrosin induces internalization and degradation of EGFR and ErbB2 in HT-29 human colon cancer cells. Cancer Lett. 2010 Jul 1;293(1):23-30.

密度	1.3±0.1 g/cm3
沸点	623.4±55.0 °C at 760 mmHg
熔点	198° (218-220°)
分子式	C₂₃H₂₂O₇
分子量	410.417
闪点	219.3±25.0 °C
精确质量	410.136566
PSA	83.45000
LogP	4.48
蒸汽压	0.0±1.9 mmHg at 25°C
折射率	1.614
储存条件	?20°C

灰叶草素, 羟基鱼藤素MSDS英文版

符号	GHS09
信号词	Warning
危害声明	H410
警示性声明	P273-P501
危害码 (欧洲)	N
风险声明 (欧洲)	50
安全声明 (欧洲)	61
危险品运输编码	UN 3077 9 / PGIII

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灰叶草素, 羟基鱼藤素下游产品? 1
CAS号522-17-8 鱼藤素

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灰叶草素, 羟基鱼藤素下游产品? 1

CAS号522-17-8
鱼藤素

[Rotenoids from Derris trifoliata].

Zhong Yao Cai 30(6) , 660-2, (2007)

Five rotenoids named dehydrodeguelin, dehydrorotenone, 12a-hydroxy rotenone, tephrosin and 12alphabeta-hydroxyrot-2′-enonic acid were isolated from aerial parts of Derris trifoliata. All these compoun…

Preparative isolation and purification of three rotenoids and one isoflavone from the seeds of Millettia pachycarpa Benth by high-speed counter-current chromatography.

J. Chromatogr. A. 1178(1-2) , 101-7, (2008)

Both analytical and preparative high-speed counter-current chromatography (HSCCC) were used to isolate and separate chemical bioactive constituents from the seeds of Millettia pachycarpa Benth, a famo…

Effect of rotenoids from the seeds of Millettia dura on larvae of Aedes aegypti.

Pest Manag. Sci. 59(10) , 1159-61, (2003)

A crude chloroform extract of seeds of Millettia dura Dunn (Leguminosae) showed high activity (LC50 = 3.5 microg ml(-1) at 24 h) against second-instar larvae of the mosquito, Aedes aegypti L (Diptera:…

Tephrosin

Toxicarol

(7aR,13aR)-7a-Hydroxy-9,10-dimethoxy-3,3-dimethyl-13,13a-dihydro-3H-chromeno[3,4-b]pyrano[2,3-h]chromen-7(7aH)-one

3H-Bis(1)benzopyrano(3,4-b:6′,5′-e)pyran-7(7aH)-one, 13,13a-dihydro-7a-hydroxy-9,10-dimethoxy-3,3-dimethyl-, (7aR,13aR)-

3H-Bis(1)benzopyrano(3,4-b:6′,5′-e)pyran-7(7aH)-one, 13,13a-dihydro-7a-hydroxy-9,10-dimethoxy-3,3-dimethyl-, (7aR-cis)-

Hydroxydeguelin

(7aR-cis)-13,13a-Dihydro-7a-hydroxy-9,10-dimethoxy-3,3-dimethyl-3H-bis[1]benzopyrano[3,4-b:6',5'-e]pyran-7(7aH)-one

3H-[1]Benzopyrano[3,4-b]pyrano[2,3-h][1]benzopyran-7(7aH)-one, 13,13a-dihydro-7a-hydroxy-9,10-dimethoxy-3,3-dimethyl-, (7aR,13aR)-

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灰叶草素, 羟基鱼藤素

品牌商品推荐

盐酸石蒜碱

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5-(3-chlorophenyl)piperidin-2-one

DL-色氨酸

5,8,9,10,14-Pentaacetoxy-3-benzoyloxy-15-hydroxypepluane

4-(4-氯苯基)-4-[4-(1H-吡唑-4-基)苯基]哌啶

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