描述 |
Pinostrobin 是一种黄酮类化合物,可在许多植物中发现,并具有抗氧化,抗炎,抗癌和神经保护的特性。 Pinostrobin 是一种有效的 PCSK9 抑制剂,可抑制 PCSK9 的催化活性。Pinostrobin 是一种有前景的胆固醇调节和脂质管理剂。 |
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相关类别 |
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靶点 |
IC50: PCSK9[1]
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SMILES |
O=C1C[C@@H](C2=CC=CC=C2)OC3=CC(OC)=CC(O)=C13 |
参考文献 |
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密度 | 1.3±0.1 g/cm3 |
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沸点 | 494.9±45.0 °C at 760 mmHg |
熔点 | 100?C |
分子式 | C16H14O4 |
分子量 | 270.280 |
闪点 | 188.8±22.2 °C |
精确质量 | 270.089203 |
PSA | 55.76000 |
LogP | 4.11 |
蒸汽压 | 0.0±1.3 mmHg at 25°C |
折射率 | 1.612 |
符号 |
GHS07 |
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信号词 |
Warning |
危害声明 |
H315-H319-H335 |
警示性声明 |
P261-P305 + P351 + P338 |
个人防护装备 |
dust mask type N95 (US);Eyeshields;Gloves |
危害码 (欧洲) |
Xi: Irritant; |
风险声明 (欧洲) |
R36/37/38 |
安全声明 (欧洲) |
S26-S36 |
危险品运输编码 | NONH for all modes of transport |
WGK德国 | 3 |
海关编码 | 2932999099 |
海关编码 | 2932999099 |
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中文概述 | 2932999099. 其他仅含氧杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0% |
申报要素 | 品名, 成分含量, 用途 |
Summary | 2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
Phloroglucinols from anti-microbial deposit-resins of Australian stingless bees (Tetragonula carbonaria). Phytother Res. 29(1) , 48-58, (2015)
Stingless bees accumulate deposits of plant resins that are mixed with beeswax to produce propolis. Previous studies have reported anti-microbial constituents of stingless bee (Tetragonula carbonaria)…
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Study on the constituents of Mexican propolis and their cytotoxic activity against PANC-1 human pancreatic cancer cells. J. Nat. Prod. 73 , 623-7, (2010)
Three new flavonoids, (2R,3R)-3,5-dihydroxy-7-methoxyflavanone 3-(2-methyl)butyrate (1), (7”R)-8-[1-(4'-hydroxy-3'-methoxyphenyl)prop-2-en-1-yl]chrysin (2), and (7”R)-8-[1-(4′-hydroxy-3′-methoxyphen…
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Cytotoxic flavonoids from the leaves of Cryptocarya chinensis. J. Nat. Prod. 73 , 1470-5, (2010)
Bioassay-guided fractionation led to the isolation of six new tetrahydroflavanones, cryptochinones A-F (1-6), from the neutral CHCl(3) fraction of Cryptocarya chinensis leaves, together with 14 known …
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Dihydrotectochrysin |
4H-1-Benzopyran-4-one, 2,3-dihydro-5-hydroxy-7-methoxy-2-phenyl-, (S)- |
Pinostrobin |
2-Phenyl-5-hydroxy-7-methoxy-2,3-dihydro-4H-1-benzopyran-4-one |
(S)-5-Hydroxy-7-methoxy-2-phenyl-2,3-dihydro-4H-chromen-4-one |
Pistrobin |
Pinocembrin-7-methyl ether |
5-Hydroxy-7-methoxy-2-phenyl-chroman-4-one |
(2S)-5-Hydroxy-7-methoxy-2-phenyl-2,3-dihydro-4H-chromen-4-one |
2,3-Dihydro-5-hydroxy-7-methoxy-2-phenyl-4H-1-benzopyran-4-one |
Pinostobin |
4H-1-Benzopyran-4-one, 2,3-dihydro-5-hydroxy-7-methoxy-2-phenyl-, (2S)- |