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甲基泼尼松龙琥珀酸钠

甲基泼尼松龙琥珀酸钠

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?甲基泼尼松龙琥珀酸钠名称


















中文名

甲基泼尼松龙琥珀酸钠
英文名

6α-Methylprednisolone 21-hemisuccinate sodium salt
中文别名


甲强龙琥珀酸钠




|



6α-甲基泼尼松龙半瑚珀酸酯



英文别名
更多





?甲基泼尼松龙琥珀酸钠生物活性










































描述
6α-Methylprednisolone 21-hemisuccinate钠盐是一种糖皮质激素, 半衰期较Prednisolone长,是一种有效的抗炎剂。
相关类别



溶解度

体外:

DMSO:≥25mg / mL(50.35 mM)

* “≥”表示可溶,但饱和度未知。


储备液

1 mM 2.0140 mL 10.0699 mL 20.1398 mL
5 mM 0.4028 mL 2.0140 mL 4.0280 mL
10 mM 0.2014 mL 1.0070 mL 2.0140 mL


存储

粉末 -20℃下 3年
4℃下 2年
在溶剂中 -80℃下 6个月
-20℃下 1个月


运输

室温;可能会有所不同
SMILES

C[C@@]12[C@](C(COC(CCC([O-])=O)=O)=O)(O)CC[C@@]1([H])[C@]3([H])C[C@H](C)C4=CC(C=C[C@]4(C)[C@@]3([H])[C@@H](O)C2)=O.[Na+]
相关活性
小分子




磺丁醚-beta-环糊精



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环孢菌素



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2,7-二氯二氢代荧光黄二醋酸



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1-甲基-4-苯基-1,2,3,6-四氢吡啶盐酸盐



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4′,4”-双-2-咪唑啉-2-基对苯二丙烯酰苯胺二盐酸盐



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乙莫克舍



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TD139



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Mitoquinone甲磺酸盐



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GSK2795039



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5,5’,6,6’-四氯-1,1’,3,3’-四乙基苯并咪唑羰花青碘化物



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胞内钙荧光探针 BAPTA-AM



|

AP20187



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GKT137831



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D-虫荧光素游离酸



|

野百合碱






?甲基泼尼松龙琥珀酸钠物理化学性质































沸点 689.6?C at 760mmHg
分子式 C26H33NaO8
分子量 496.525
闪点 230.7?C
精确质量 496.207306
PSA 141.03000
LogP 0.88460
外观性状 冻干的粉末






?甲基泼尼松龙琥珀酸钠MSDS







?甲基泼尼松龙琥珀酸钠毒性和生态




甲基泼尼松龙琥珀酸钠毒性英文版






?甲基泼尼松龙琥珀酸钠安全信息




































符号

GHS08


GHS08
信号词
Danger
危害声明
H351-H360
警示性声明
P201-P281-P308 + P313
个人防护装备
Eyeshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
危害码 (欧洲)
T: Toxic;
风险声明 (欧洲)
R61;R40
安全声明 (欧洲)
53-22-36/37/39-45
危险品运输编码 NONH for all modes of transport
WGK德国 3
RTECS号 TU4154060














?甲基泼尼松龙琥珀酸钠文献25

更多文献














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?甲基泼尼松龙琥珀酸钠英文别名
















































MFCD00152612


11b,17,21-Trihydroxy-6a-methylpregna-1,4-diene-3,20-dione 21-(Sodium Succinate)


butanedioic acid, mono[(6α,11β)-11,17-dihydroxy-6-methyl-3,20-dioxopregna-1,4-dien-21-yl] ester, monosodium salt


4-{2-[(6S,8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-6,10,13-triméthyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodécahydro-3H-cyclopenta[a]phénanthrén-17-yl]-2-oxoéthoxy}-4-oxobutanoate de sodium


6alpha-Methylprednisolone sodium succinate


Sodium 4-{[(6α,11β)-11,17-dihydroxy-6-methyl-3,20-dioxopregna-1,4-dien-21-yl]oxy}-4-oxobutanoate


6a-Methylprednisolone 21-succinate sodium


EINECS 219-156-8


Methylprednisolone sodium succinate


Natrium-4-{2-[(6S,8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-6,10,13-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl]-2-oxoethoxy}-4-oxobutanoat


Butanedioic acid, mono[(6α,11β)-11,17-dihydroxy-6-methyl-3,20-dioxopregna-1,4-dien-21-yl] ester, sodium salt (1:1)


sodium 4-{2-[(6S,8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-6,10,13-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl]-2-oxoethoxy}-4-oxobutanoate


6α-Methylprednisolone 21-hemisuccinate (sodium salt)








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