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番泻苷D

番泻苷D

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?番泻苷D名称


















中文名

番泻苷D
英文名

Sennoside D
中文别名


番泻苷 D



英文别名
更多





?番泻苷D生物活性


































描述
Sennoside D 是一种蒽醌苷,在番泻叶 (Cassia angustifolia) 的叶子和豆荚中发现。
相关类别



SMILES

OC1=CC(C(O)=O)=CC([C@@]([C@](C2=CC=CC(O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)=C2C4=O)([H])C5=C4C(O)=CC(CO)=C5)([H])C6=CC=CC(O[C@@H]7O[C@H](CO)[C@@H](O)[C@H](O)[C@H]7O)=C86)=C1C8=O
参考文献

[1]. Rama Reddy NR, et al. Next Generation Sequencing and Transcriptome Analysis Predicts Biosynthetic Pathway of Sennosides from Senna (Cassia angustifolia Vahl.), a Non-Model Plant with Potent Laxative Properties. PLoS One. 2015 Jun 22;10(6):e0129422.







?番泻苷D物理化学性质





































密度 1.7±0.1 g/cm3
沸点 1130.3±65.0 °C at 760 mmHg
分子式 C42H40O19
分子量 848.756
闪点 344.4±27.8 °C
精确质量 848.216370
PSA 330.89000
LogP 0.68
蒸汽压 0.0±0.3 mmHg at 25°C
折射率 1.758
储存条件 2-8°C






?番泻苷D安全信息
















危险品运输编码 NONH for all modes of transport














?番泻苷D文献3

更多文献














Potentiating effect of sennoside C on purgative activity of sennoside A in mice.

Planta Med. 42(3) , 302-3, (1981)





The synergistic purgative action of aloe-emodin anthrone and rhein anthrone in mice: synergism in large intestinal propulsion and water secretion.

J. Pharm. Pharmacol. 49(1) , 22-5, (1997)

This study aimed to explore the mechanism involved in the synergistic purgative action of aloe-emodin anthrone and rhein anthrone, the active metabolites of sennoside C. Aloe-emodin anthrone and rhein…





Metabolic activation of sennoside C in mice: synergistic action of anthrones.

J. Pharm. Pharmacol. 44(12) , 973-6, (1992)

Sennosides A and C directly injected into the caecum of mice showed equal purgative activity. Intracaecal administration reduced time to onset of diarrhoea induced by sennoside C from about 3 h after …









?番泻苷D英文别名


















(9R,9′S)-5,5′-Bis(β-D-glucopyranosyloxy)-4,4′-dihydroxy-2′-(hydroxymethyl)-10,10′-dioxo-9,9′,10,10′-tetrahydro-9,9′-bianthracene-2-carboxylic acid


[9,9'-Bianthracene]-2-carboxylic acid, 5,5′-bis(β-D-glucopyranosyloxy)-9,9′,10,10′-tetrahydro-4,4′-dihydroxy-2′-(hydroxymethyl)-10,10′-dioxo-, (9R,9′S)-


SennosideD








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