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益康唑

益康唑

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?益康唑名称


















中文名

益康唑
英文名

Econazole
中文别名


1-[2-[(4-氯苯基)甲氧基]-2-(2,4-二氯苯基)乙基]-1H-咪唑




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1-[2,4-二氯-2-(4-氯苄氧基)苯乙基]咪唑




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双氯甲氧苯咪唑



英文别名
更多





?益康唑生物活性












































描述
Econazole是一抗真菌化合物。
相关类别



溶解度

体外:

在DMSO中10mM


储备液

1 mM 2.6200 mL 13.1000 mL 26.2000 mL
5 mM 0.5240 mL 2.6200 mL 5.2400 mL
10 mM 0.2620 mL 1.3100 mL 2.6200 mL


存储

请将产品存放在分析证书中的建议条件下。


运输

室温;可能会有所不同
SMILES

ClC1=CC=C(C(OCC2=CC=C(Cl)C=C2)CN3C=CN=C3)C(Cl)=C1
参考文献

[1]. Thienpont D, et al. Bilogical and toxicological properties of econazole, a broad-spectrum antimycotic. Arzneimittelforschung. 1975 Feb;25(2):224-30.


相关活性
小分子




放线菌酮



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潮霉素B



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醋酸卡泊芬净



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5-氟胞嘧啶



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泊沙康唑



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特比萘芬



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环吡酮胺



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艾沙康唑



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阿尼芬净



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克霉唑



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氯碘羟喹



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硝酸咪康唑



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纳他霉素



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长川霉素



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硝酸益康唑






?益康唑物理化学性质





































密度 1.3±0.1 g/cm3
沸点 533.8±50.0 °C at 760 mmHg
熔点 86.8?C
分子式 C18H15Cl3N2O
分子量 381.684
闪点 276.6±30.1 °C
精确质量 380.024994
PSA 27.05000
LogP 5.32
蒸汽压 0.0±1.4 mmHg at 25°C
折射率 1.615






?益康唑MSDS







?益康唑毒性和生态




益康唑毒性英文版






?益康唑安全信息




















危害码 (欧洲)
Xi
风险声明 (欧洲)
R36/37/38
安全声明 (欧洲)
24/25-36/37/39














?益康唑文献31

更多文献














The use of ammonium hydroxide as an additive in supercritical fluid chromatography for achiral and chiral separations and purifications of small, basic medicinal molecules.

J. Chromatogr. A. 1218(43) , 7886-94, (2011)

This study describes using 0.1% of a 28-30% ammonium hydroxide solution as an additive to alcohol modifiers in SFC to improve chromatographic peak shapes for basic molecules. Ammonium hydroxide’s high…





A method to identify and validate mitochondrial modulators using mammalian cells and the worm C. elegans.

Sci. Rep. 4 , 5285, (2014)

Mitochondria are semi-autonomous organelles regulated by a complex network of proteins that are vital for many cellular functions. Because mitochondrial modulators can impact many aspects of cellular …





Effect of methoxychlor on Ca(2+) movement and viability in MDCK renal tubular cells.

Basic Clin Pharmacol Toxicol. 111(4) , 224-31, (2012)

The effect of the insecticide methoxychlor on the physiology of renal tubular cells is unknown. This study aimed to explore the effect of methoxychlor on cytosolic Ca(2+) concentrations ([Ca(2+) ](i) …









?益康唑英文别名


































































1-{2-[(4-Chlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole


1-[2,4-Dichloro-b-[(p-chlorobenzyl)oxy]phenethyl]imidazole


1-[2-[(4-Chlorophenyl)methoxy]-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole


EINECS 248-341-6


Econazole


Ecostatin


Imidazole, 1-(2,4-dichloro-β-((p-chlorobenzyl)oxy)phenethyl)-


Gyno-Pevaryl


1H-Imidazole, 1-(2-((4-chlorophenyl)methoxy)-2-(2,4-dichlorophenyl)ethyl)-


UNII:6Z1Y2V4A7M


Spectazole


Palavale


1-{2-(4-chlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl}imidazole


Epi-pevaryl


Ifenec


econazolum


Pevaryl


1H-Imidazole, 1-[2-[(4-chlorophenyl)methoxy]-2-(2,4-dichlorophenyl)ethyl]-


MFCD00800993








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