中文名 |
盐酸二氟沙星 |
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英文名 |
Difloxacin Hydrochloride Salt |
中文别名 |
双氟沙星盐酸盐 | 二氟沙星/1-(4-氟苯基)-6-氟-4-氧代-1,4-二氢-7-(4-甲基-1-哌嗪基)-3-喹啉羧酸盐酸盐 | 6-氟-1-(4-氟苯基)-7-(4-甲基哌嗪-1-基)-4-氧代喹啉-3-羧酸盐酸盐 | 盐酸双氟沙星 |
英文别名 |
更多 |
描述 |
Difloxacin hydrochloride 是一种广谱抗菌药物。Difloxacin hydrochloride 通过干扰 DNA 促旋酶和拓扑异构酶 IV 的活性可抑制细菌 DNA 促旋酶和显示出浓度依赖性的杀菌作用。 |
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相关类别 |
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SMILES |
O=C(C1=CN(C2=CC=C(F)C=C2)C3=C(C=C(F)C(N4CCN(C)CC4)=C3)C1=O)O.[H]Cl |
参考文献 |
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密度 | 1.409 g/cm3 |
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沸点 | 595.5?C at 760 mmHg |
熔点 | >245?C (dec.) |
分子式 | C21H20ClF2N3O3 |
分子量 | 435.852 |
闪点 | 313.9?C |
精确质量 | 435.116119 |
PSA | 65.78000 |
LogP | 3.52380 |
外观性状 | 灰白色至淡黄色固体 |
折射率 | 1.629 |
储存条件 | 0-6°C |
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个人防护装备 |
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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危险品运输编码 | NONH for all modes of transport |
RTECS号 | VB2008975 |
Determination of fluoroquinolones in chicken feces – a new liquid-liquid extraction method combined with LC-MS/MS. Environ. Toxicol. Pharmacol. 38(3) , 792-9, (2014)
The application of antibiotics including fluoroquinolones to farming animals is widespread and may lead to the development of antibiotic resistance and other environmental effects. To calculate enviro…
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Occurrence and distribution of antibiotics in urban soil in Beijing and Shanghai, China. Environ. Sci. Pollut. Res. Int. 22 , 11360-71, (2015)
The recycling of reclaimed wastewater for irrigation and road cleaning is an important strategy to minimize water scarcity in megacities. However, little is known regarding the potential accumulation …
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Facile synthesis of polyaniline-coated SiO? nanofiber and its application in enrichment of fluoroquinolones from honey samples. Talanta 140 , 29-35, (2015)
In this study, polyaniline coated SiO2 nanofibers (PANI/SiO2) was prepared by combining electrospinning technique with in-situ polymerization. The proposed strategy for the preparation of PANI/SiO2 ca…
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MFCD03840489 |
6-fluoro-1-(4-fluorophenyl)-7-(4-methylpiperazin-1-yl)-4-oxoquinoline-3-carboxylic acid,hydrochloride |