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盐酸吐根酚碱

盐酸吐根酚碱

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?盐酸吐根酚碱名称


















中文名

盐酸吐根酚碱
英文名

cephaeline hydrochloride
中文别名


吐根酚碱盐酸盐(七水)



英文别名
更多





?盐酸吐根酚碱生物活性






































描述
盐酸头孢菌素((-)-盐酸头孢菌素)是印度吐根中的一种酚性生物碱。盐酸头孢喹对寨卡病毒(ZIKV)和埃博拉病毒(EBOV)感染均具有有效的抑制作用[1][2]。
相关类别




存储

请将产品存放在分析证书中的建议条件下。


运输

室温
SMILES

OC1=CC2=C([C@@H](C[C@@H]3[C@@H](CC)CN4CCC5=CC(OC)=C(OC)C=C5[C@]4([H])C3)NCC2)C=C1OC.[H]Cl
参考文献

[1]. N.P.Sahu, et al. Determination of emetine and cephaeline in Ipecac roots by high- performance liquid chromatography. Journal of Chromatography A. 1982 Apr; 238( 2):525-529.

[2]. Yang S, et al. Emetine inhibits Zika and Ebola virus infections through two molecular mechanisms: inhibiting viral replication and decreasing viral entry. Cell Discov. 2018 Jun 5;4:31.







?盐酸吐根酚碱物理化学性质






















分子式 C28H40Cl2N2O4
分子量 539.534
精确质量 538.236511
PSA 63.19000
LogP 6.51110
















?盐酸吐根酚碱英文别名






















































10,11,7′-Trimethoxy-emetan-6′-ol,Hydrochlorid


AC1NUT82


CHEBI:2535


(2R,3R,11bS)-(+)-2-(3,4-dihydro-6-hydroxy-7-methoxy-1-isoquinolyl)methyl-3-ethyl-1,3,4,6,7,11b-hexahydro-8-hydroxy-9,10-dimethoxy-2H-benzo[a]quinolizine (alangicine)


Alangicine


7′,10,11-Trimethoxyemetan-6′-ol dihydrochloride


2-(6-hydroxy-7-methoxy-3,4-dihydro-isoquinolin-1-ylmethyl)-3-ethyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-8-ol


Cephaeline dihydrochloride


10,11,7′-trimethoxy-emet-1′-ene-9,6′-diol


Emetan-6′-ol, 7′,10,11-trimethoxy-, dihydrochloride (9CI)


10,11,7′-trimethoxy-emetan-6′-ol,dihydrochloride


(2R,3R,11bS)-3-ethyl-2-(6-hydroxy-7-methoxy-3,4-dihydroisoquinolin-1-ylmethyl)-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-8-ol


6-Isoquinolinol, 1-[[(2S,3R,11bS)-3-ethyl-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-2H-benzo[a]quinolizin-2-yl]methyl]-1,2,3,4-tetrahydro-7-methoxy-, (1R)-, hydrochloride (1:2)


10,11,7′-Trimethoxy-emetan-6′-ol,Dihydrochlorid


Emetan-6′-ol, 7′,10,11-trimethoxy-, dihydrochloride








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