盐酸头孢噻呋

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中文名	盐酸头孢噻呋
英文名	Ceftiofur Hydrochloride
中文别名	(6R,7R)-7-[2-(2-氨基噻唑-4-基)(甲氧基亚胺基)乙酰胺基]-3-[(2-呋喃基羰基)硫甲基]-8-氧代-5-硫杂-1-氮杂双环[4.2.0]辛-2-烯-3-甲酸盐酸盐 \| (6R,7R)-7-[2-(2-氨基噻唑-4-基)(甲氧基亚胺基)乙酰胺基]-3-[(2-呋喃基羰基)硫甲基]-8-氧代-5-硫杂-1-氮杂双环[4.2.0]辛-2-烯-3-甲酸盐酸盐 \| (6R,7R)-7-[2-(2-氨基噻唑-4-基)(甲氧基亚胺基)乙酰胺基]-3-[(2-呋喃基羰基)硫甲基]-8-氧代-5-硫杂-1-氮杂双环[4.2.0]辛-2-烯-2-甲酸盐酸盐 \| 头孢噻呋盐酸盐
英文别名	更多

描述	Ceftiofur hydrochloride 是一种半合成抗生素，对针对家畜的各种革兰氏阳性和革兰氏阴性菌、好氧菌和厌氧菌均有抗菌活性。
相关类别	研究领域 >> 感染信号通路 >> 抗感染 >> 细菌
靶点	bacterial[1]
SMILES	[H]Cl.O=C(C(N12)=C(CSC(C3=CC=CO3)=O)CS[C@]2([H])[C@H](NC(/C(C4=CSC(N)=N4)=NOC)=O)C1=O)O
参考文献	[1]. Fernández-Varón E, et al. Pharmacokinetics (PK), pharmacodynamics (PD), and PK-PD integration of ceftiofur after a single intravenous, subcutaneous and subcutaneous-LA administration in lactating goats. BMC Vet Res. 2016 Oct 13;12(1):232.

沸点	814.1?C at 760 mmHg
熔点	>190°C (dec.)
分子式	C₁₉H₁₈ClN₅O₇S₃
分子量	560.023
闪点	446.1?C
精确质量	559.005676
PSA	256.26000
LogP	2.69300
外观性状	灰白色固体
蒸汽压	5.14E-28mmHg at 25°C
储存条件	-20°C Freezer

危险品运输编码	NONH for all modes of transport
海关编码	2941905990

海关编码	2941905990

blaCTX-M-32 on an IncN plasmid in Escherichia coli from beef cattle in the United States.

Antimicrob. Agents Chemother. 57(2) , 1096-7, (2013)

Genetic merit for fertility traits in Holstein cows: V. Factors affecting circulating progesterone concentrations.

J. Dairy Sci. 97(9) , 5543-57, (2014)

This study investigated the factors affecting circulating progesterone (P4) concentrations in cows with similar genetic merit for milk production traits, but with extremes of good (Fert+) or poor (Fer…

Lipase is essential for the study of in vitro release kinetics from organogels.

Mol. Pharm. 9(6) , 1803-11, (2012)

In vitro drug release studies remain indispensable in the development of drug delivery systems, even if correlations between in vitro and in vivo results are often imperfect. In this work, an improved…

Ceftiofur Hydrochloride

(6R,7R)-7-{[(2Z)-2-(2-Amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-[(2-furoylsulfanyl)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid hydrochloride (1:1)

Ceftiofur HCl

5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2Z)-2-(2-amino-4-thiazolyl)-2-(methoxyimino)-1-oxoethyl]amino]-3-[[(2-furanylcarbonyl)thio]methyl]-8-oxo-, (6R,7R)-, hydrochloride (1:1)

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盐酸头孢噻呋

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