硫酸西梭霉素

中文名	硫酸西梭霉素
英文名	Sisomicin sulfate
中文别名	硫酸西索紫苏 \| 硫酸西梭米星/硫酸西索霉素 \| 硫酸西梭米星 \| 硫酸西索米星
英文别名	更多

描述

Sisomicin硫酸盐是一种氨基糖苷类抗生素。

相关活性
小分子

沸点	676.6?C at 760mmHg
熔点	70-73?C
分子式	C₁₉H₃₇N₅O₇ _. ₅/₂ H₂SO₄
分子量	692.72
闪点	363?C
PSA	842.34000
LogP	0.82120
外观性状	white to off-white
储存条件	库房通风低温干燥,与食品原料分开存放
水溶解性	H2O: soluble50mg/mL \| Soluble in water

硫酸西梭霉素毒性英文版

符号	GHS07, GHS08
信号词	Danger
危害声明	H312 + H332-H360
警示性声明	P201-P261-P280-P308 + P313
个人防护装备	Eyeshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
危害码 (欧洲)	T,Xi
风险声明 (欧洲)	61-20/21/22-36/37/38
安全声明 (欧洲)	53-22-36/37/39-45-36-26
危险品运输编码	NONH for all modes of transport
WGK德国	3
RTECS号	WK2288000

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硫酸西梭霉素下游产品? 1
CAS号32385-11-8 西梭米星

硫酸西梭霉素上游产品? 0

硫酸西梭霉素下游产品? 1

CAS号32385-11-8
西梭米星

Determination of equilibrium constant of amino carbamate adduct formation in sisomicin by a high pH based high performance liquid chromatography.

J. Pharm. Biomed. Anal. 111 , 126-30, (2015)

Amino carbamate adduct formation from the amino group of an aminoglycoside and carbon dioxide has been postulated as a mechanism for reducing nephrotoxicity in the aminoglycoside class compounds. In t…

Biomimetic synthesis and structural refinement of the macrocyclic dimer aminoglycoside 66-40C–the remarkably selective self-condensation of a putative aldehyde intermediate in the submerged culture medium producing sisomicin.

Chem. Commun. (Camb.) 46(12) , 2013-5, (2010)

Aminoglycoside 66-40C, an unprecedented 16-membered bis-azadiene macrocyclic natural product isolated from the Micromonospora producer of the antibiotic sisomicin, was synthesized following a biomimet…

Pharmacokinetics and safety of single and multiple doses of ACHN-490 injection administered intravenously in healthy subjects.

Antimicrob. Agents Chemother. 55(12) , 5874-80, (2011)

ACHN-490 is an aminoglycoside with activity against multidrug-resistant pathogens, including those resistant to currently used aminoglycosides. Two randomized, double-blind, placebo-controlled clinica…

Extramycin

Siseptin

Pathomycin

sisomicin sulfate

Antibiotic 66-40 sulfate

O-3-Deoxy-4-C-methyl-3-(methylamino)-b-L-arabinopyranosyl(1?6)-O-[2,6-diamino-2,3,4,6-tetradeoxy-a-D-glycero-hex-4-enopyranosyl-(1?4)]-2-deoxy-D-streptamine Sulfate (2:5) (Salt)

Sch 13475 sulfate

(1S,2S,3R,4S,6R)-4,6-Diamino-3-{[3-amino-6-(aminomethyl)-3,4-dihydro-2H-pyran-2-yl]oxy}-2-hydroxycyclohexyl 3-deoxy-4-C-methyl-3-(methylamino)-β-L-arabinopyranoside sulfate (2:5)

(2S-cis)-4-O-[3-Amino-6-(aminomethyl)-3,4-dihydro-2H-pyran-2-yl]-2-deoxy-6-O-[3-deoxy-4-C-methyl-3-(methylamino)-b-L-arabinopyranosyl]-D-streptamine Sulfate (2:5) (Salt)

Mensiso

Sisomycin sulfate

Sisomin

β-L-Arabinopyranoside, (1S,2S,3R,4S,6R)-4,6-diamino-3-[[3-amino-6-(aminomethyl)-3,4-dihydro-2H-pyran-2-yl]oxy]-2-hydroxycyclohexyl 3-deoxy-4-C-methyl-3-(methylamino)-, sulfate (2:5) (salt)

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