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碘帕醇

碘帕醇

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?碘帕醇名称


















中文名

碘帕醇
英文名

(S)-N,N′-Bis[2-hydroxy-1-(hydroxymethyl)ethyl]-2,4,6-triiodo-5-lactamidoisophthalamide
中文别名


(S)-N,N’-双(1,3-二羟基丙-2-基)-5-[[(2S)-2-羟基丙酰]氨基]-2,4,6-三碘苯-1,3-二甲酰胺



英文别名
更多





?碘帕醇生物活性












































描述
Iopamidol (B-15000; SQ-13396) 是非离子型,低渗透碘化造影剂。
相关类别



溶解度

体外:

H 2 O:≥8.2mg / mL(10.55 mM)

* “≥”表示可溶,但饱和度未知。


储备液

1 mM 1.2869 mL 6.4343 mL 12.8685 mL
5 mM 0.2574 mL 1.2869 mL 2.5737 mL
10 mM 0.1287 mL 0.6434 mL 1.2869 mL


存储

4°C,避光


运输

室温;可能会有所不同
SMILES

O=C(C1=C(I)C(NC([C@@H](O)C)=O)=C(I)C(C(NC(CO)CO)=O)=C1I)NC(CO)CO
参考文献

[1]. https://en.wikipedia.org/wiki/Iopamidol


相关活性
小分子




磺丁醚-beta-环糊精



|

环孢菌素



|

2,7-二氯二氢代荧光黄二醋酸



|

1-甲基-4-苯基-1,2,3,6-四氢吡啶盐酸盐



|

4′,4”-双-2-咪唑啉-2-基对苯二丙烯酰苯胺二盐酸盐



|

乙莫克舍



|

TD139



|

Mitoquinone甲磺酸盐



|

GSK2795039



|

5,5’,6,6’-四氯-1,1’,3,3’-四乙基苯并咪唑羰花青碘化物



|

胞内钙荧光探针 BAPTA-AM



|

AP20187



|

GKT137831



|

D-虫荧光素游离酸



|

野百合碱






?碘帕醇物理化学性质











































密度 2.3±0.1 g/cm3
沸点 785.3±60.0 °C at 760 mmHg
熔点 >320?C (dec)
分子式 C17H22I3N3O8
分子量 777.085
闪点 428.8±32.9 °C
精确质量 776.854065
PSA 188.45000
LogP -2.09
外观性状 白色结晶粉末
蒸汽压 0.0±2.9 mmHg at 25°C
折射率 1.739
储存条件 -20?C Freezer





?碘帕醇毒性和生态




碘帕醇毒性英文版






?碘帕醇安全信息


















危险品运输编码 NONH for all modes of transport
海关编码 2924299090





?碘帕醇合成线路





















~96%







碘帕醇结构式

碘帕醇

60166-93-0






文献:EP883597 B1, ; Page/Page column 6-7 ;





~%







碘帕醇结构式

碘帕醇

60166-93-0






文献:WO2012/175903 A1, ;







?碘帕醇上下游产品











碘帕醇上游产品? 3

碘帕醇下游产品? 0










?碘帕醇海关















海关编码 2924299090
中文概述 2924299090. 其他环酰胺(包括环氨基甲酸酯)(包括其衍生物以及他们的盐). 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%
申报要素 品名, 成分含量, 用途, 包装
Summary 2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%








?碘帕醇文献35

更多文献














Low contrast and radiation dose coronary CT angiography using a 320-row system and a refined contrast injection and timing method.

J. Cardiovasc. Comput. Tomogr. 9(1) , 19-27, (2015)

Among CT scanners, 320-row instruments feature decreased photon energy and yield strong contrast enhancement. Consequently, the contrast medium (CM) dose can be reduced. The results of low-tube-voltag...





Influence of the motion correction algorithm on the quality and interpretability of images of single-source 64-detector coronary CT angiography among patients grouped by heart rate.

Jpn. J. Radiol. 33(2) , 84-93, (2015)

We retrospectively investigated the effect of the motion correction algorithm (MCA) on image quality and interpretability by heart rate (HR) in coronary CT angiography (CCTA).For 105 patients (6 HR gr...





Evaluation of the predictive value of coronary artery calcium score for obstructive coronary artery disease in asymptomatic Korean patients with type 2 diabetes mellitus.

Coron. Artery Dis. 26(2) , 150-6, (2015)

Compared with coronary computed tomographic angiography (CCTA), the coronary artery calcium score (CACS) may be limited in predicting adverse cardiovascular events in asymptomatic diabetic patients.We...









?碘帕醇英文别名





























































































1,3-benzenedicarboxamide, N,N'-bis[2-hydroxy-1-(hydroxymethyl)ethyl]-5-[[(2S)-2-hydroxy-1-oxopropyl]amino]-2,4,6-triiodo-


UNII:JR13W81H44


1,3-benzenedicarboxamide, N,N’-bis[2-hydroxy-1-(hydroxymethyl)ethyl]-5-[(2-hydroxy-1-oxopropyl)amino]-2,4,6-triiodo-


N,N’-Bis(1,3-dihydroxy-2-propanyl)-2,4,6-triiodo-5-(lactoylamino)isophthalamide


N,N’-Bis(1,3-dihydroxy-2-propanyl)-5-{[(2S)-2-hydroxypropanoyl]amino}-2,4,6-triiodoisophthalamide


Iopamiron


EINECS 262-093-6


N,N’-bis[2-hydroxy-1-(hydroxyméthyl)éthyl]-5-{[(2S)-2-hydroxypropanoyl]amino}-2,4,6-triiodobenzène-1,3-dicarboxamide


(S)-N,N’-Bis[2-hydroxy-1-(hydroxymethyl)ethyl]-2,4,6-triiodo-5-lactamidoisophthalamide


1,3-benzenedicarboxamide, N1,N3-bis[2-hydroxy-1-(hydroxymethyl)ethyl]-5-[[(2S)-2-hydroxy-1-oxopropyl]amino]-2,4,6-triiodo-


N,N’-Bis[2-hydroxy-1-(hydroxymethyl)ethyl]-5-{[(2S)-2-hydroxypropanoyl]amino}-2,4,6-triiodbenzol-1,3-dicarboxamid


1,3-Benzenedicarboxamide, N,N-bis[2-hydroxy-1-(hydroxymethyl)ethyl]-5-[(2-hydroxy-1-oxopropyl)amino]-2,4,6-triiodo-


N,N’-bis[2-hydroxy-1-(hydroxymethyl)ethyl]-5-{[(2S)-2-hydroxypropanoyl]amino}-2,4,6-triiodobenzene-1,3-dicarboxamide


Iopamidol


1,3-Benzenedicarboxamide, N,N’-bis(2-hydroxy-1-(hydroxymethyl)ethyl)-5-((2-hydroxy-1-oxopropyl)amino)-2,4,6-triiodo-


Isovue


MFCD00867931


1,3-Benzenedicarboxamide, N,N-bis[2-hydroxy-1-(hydroxymethyl)ethyl]-5-[[(2S)-2-hydroxy-1-oxopropyl]amino]-2,4,6-triiodo-


5-(a-Hydroxypropionylamino)-2,4,6-triiodoisophthalic Acid Di(1,3-dihydroxyisopropylamide)


Iopamiro


N,N’-bis[2-hydroxy-1-(hydroxymethyl)ethyl]-5-[(2-hydroxypropanoyl)amino]-2,4,6-triiodobenzene-1,3-dicarboxamide


(s)-n,n’-bis(2-hydroxy-1-(hydroxymethyl)ethyl)-2,4,6-triiodo-5-lactamidoisophthalamide


N,N’-bis(1,3-dihydroxypropan-2-yl)-5-{[(2S)-2-hydroxypropanoyl]amino}-2,4,6-triiodobenzene-1,3-dicarboxamide


(S)-N,N’-Bis[2-hydroxy-1-(hydroxymethyl)ethyl]-5-[(2-hydroxy-1-oxopropyl)amino]-2,4,6-triiodo-1,3-benzenedicarboxamide


Solutrast


iomapidol


N,N’-Bis(1,3-dihydroxypropan-2-yl)-5-{[(2S)-2-hydroxypropanoyl]amino}-2,4,6-triiodoisophthalamide


Jopamiro








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