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紫云英苷

紫云英苷

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?紫云英苷名称


















中文名

紫云英苷
英文名

kaempferol 3-O-glucoside
中文别名


紫云英甙




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紫芸英苷




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黄芪苷、莰非醇-3-O-葡萄糖苷、山柰酚-3-葡萄糖苷、百蕊草素Ⅱ




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莰非醇-3-O-葡糖苷




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山奈酚-3-葡萄糖苷




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黄芪苷;紫云英甙;莰非醇-3-O-葡萄糖苷;山柰酚-3-葡萄糖苷;百蕊草素Ⅱ




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黄芪苷



英文别名
更多





?紫云英苷生物活性












































描述
紫云英苷(山奈酚-3-O-葡萄糖苷)是一种黄酮类化合物,具有抗炎活性。
相关类别




溶解度

体外:

在DMSO中10mM


储备液

1 mM 2.2303 mL 11.1513 mL 22.3025 mL
5 mM 0.4461 mL 2.2303 mL 4.4605 mL
10 mM 0.2230 mL 1.1151 mL 2.2303 mL


存储

粉末 -20°C 3年
? 4°C 2年
在溶剂中 -80°C 6月
? -20°C 1月


运输

室温;可能会有所不同
SMILES

OC1=CC2=C(C(C(O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)=C(C4=CC=C(O)C=C4)O2)=O)C(O)=C1
参考文献

[1]. Cho IH, et al. Astragalin inhibits airway eotaxin-1 induction and epithelial apoptosis through modulating oxidative stress-responsive MAPK signaling. BMC Pulm Med. 2014 Jul 29;14:122.

[2]. Li F, et al. Inhibitory effects of astragalin on lipopolysaccharide-induced inflammatory response in mouse mammary epithelial cells. J Surg Res. 2014 Dec;192(2):573-81.

[3]. Li F, et al. Astragalin suppresses inflammatory responses via down-regulation of NF-κB signaling pathway in lipopolysaccharide-induced mastitis in a murine model. Int Immunopharmacol. 2013 Oct;17(2):478-82.

[4]. Kim MS, et al. Inhibitory effect of astragalin on expression of lipopolysaccharide-induced inflammatory mediators through NF-κB in macrophages. Arch Pharm Res. 2011 Dec;34(12):2101-7.

[5]. Soromou LW, et al. Astragalin attenuates lipopolysaccharide-induced inflammatory responses by down-regulating NF-κB signaling pathway. Biochem Biophys Res Commun. 2012 Mar 9;419(2):256-61.


相关活性
小分子




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环孢菌素



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2,7-二氯二氢代荧光黄二醋酸



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1-甲基-4-苯基-1,2,3,6-四氢吡啶盐酸盐



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4′,4”-双-2-咪唑啉-2-基对苯二丙烯酰苯胺二盐酸盐



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乙莫克舍



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TD139



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Mitoquinone甲磺酸盐



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GSK2795039



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5,5’,6,6’-四氯-1,1’,3,3’-四乙基苯并咪唑羰花青碘化物



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胞内钙荧光探针 BAPTA-AM



|

AP20187



|

GKT137831



|

D-虫荧光素游离酸



|

野百合碱






?紫云英苷物理化学性质







































密度 1.8±0.1 g/cm3
沸点 823.2±65.0 °C at 760 mmHg
熔点 223-229?C
分子式 C21H20O11
分子量 448.377
闪点 291.6±27.8 °C
精确质量 448.100555
PSA 190.28000
LogP 1.95
蒸汽压 0.0±3.1 mmHg at 25°C
折射率 1.774
储存条件 ?20°C






?紫云英苷MSDS







?紫云英苷毒性和生态




紫云英苷毒性英文版






?紫云英苷安全信息




















安全声明 (欧洲)
22
危险品运输编码 NONH for all modes of transport
RTECS号 DJ3080000





?紫云英苷合成线路






















?紫云英苷文献28

更多文献














Separation of patuletin-3-O-glucoside, astragalin, quercetin, kaempferol and isorhamnetin from Flaveria bidentis (L.) Kuntze by elution-pump-out high-performance counter-current chromatography.

J. Chromatogr. A. 1218(36) , 6206-11, (2011)

Flaveria bidentis (L.) Kuntze is an annual alien weed of Flaveria Juss. (Asteraceae) in China. Bioactive compounds, mainly flavonol glycosides and flavones from F. bidentis (L.) Kuntze, have been stud…





A sensitive LC-MS/MS method for simultaneous determination of six flavonoids in rat plasma: application to a pharmacokinetic study of total flavonoids from mulberry leaves.

J. Pharm. Biomed. Anal. 84 , 189-95, (2013)

A simple and sensitive LC-MS/MS method has been developed and validated for the determination of rutin, isoquercitrin, astragalin, quercetin, kaempferol and isorhamnetin in rat plasma using naringin a…





[Study on the chemical constituets in ethyl acetante extraction from semen litchi].

Zhong Yao Cai 35(1) , 64-6, (2012)

To study the chemical constituents in ethyl acetate extraction of Semen Litchi.The compounds were isolated and purified by column chromatography on silica gel and Sephadex LH-20 coupled with preparati…









?紫云英苷英文别名














































































5,7-dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-3-yl b-D-glucopyranoside


5,7-Dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-3-yl β-D-glucopyranoside


5,7-Dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-3-yl-β-D-glucopyranoside


Kaempferol-3-O-D-glucopyranoside


4H-1-Benzopyran-4-one, 3-(β-D-glucopyranosyloxy)-5,7-dihydroxy-2-(4-hydroxyphenyl)-


Kaempferol-3-β-glucopyranoside


5,7-Dihydroxy-2-(4-hydroxyphenyl)-3-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}-4H-chromen-4-one


Kaempferol-3-O-glucoside


Kaempferol 3-O-β-D-glucoside


5,7-dihydroxy-2-(4-hydroxyphenyl)-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-4-one


kaempferol 3-O-glucoside


Astragaloside


MFCD00075932


Kaempferol-3-O-β-D-glucopyranoside


Kaempferol-3-β-monoglucoside


Kaempferol-3-D-glucoside


Kaempferol 3-O-β-D-glucopyranoside


3-Glucosylkaempferol


Astragalin


5,7-Dihydroxy-2-(4-hydroxyphényl)-3-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxyméthyl)tétrahydro-2H-pyran-2-yl]oxy}-4H-chromén-4-one


Kaempferol-3-glucoside


5,7-Dihydroxy-2-(4-hydroxyphenyl)-3-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}-4H-chromen-4-on


Kaempferol 3-glucoside



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