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| 描述 |
Zerumbone 是从Zingiber zerumbet Smith 的根茎中分离出来的单环倍半萜烯化合物。Zerumbone 有效抑制Epstein-Barr 病毒的激活，IC50 为 0.14 mM。Zerumbone 具有抗癌，抗氧化，抗炎，抗增殖的作用。 |
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| 相关类别 |
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| SMILES |
C/C1=CCC/C(C)=C/CC(C)(C)/C=C/C1=O |
| 参考文献 |
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| 密度 | 0.9±0.1 g/cm3 |
|---|---|
| 沸点 | 321.6±42.0 °C at 760 mmHg |
| 分子式 | C15H22O |
| 分子量 | 218.335 |
| 闪点 | 133.9±22.8 °C |
| 精确质量 | 218.167068 |
| PSA | 17.07000 |
| LogP | 5.34 |
| 蒸汽压 | 0.0±0.7 mmHg at 25°C |
| 折射率 | 1.468 |
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Zingiber zerumbet CYP71BA1 catalyzes the conversion of α-humulene to 8-hydroxy-α-humulene in zerumbone biosynthesis. Cell. Mol. Life Sci. 68(6) , 1033-40, (2011)
Plant cytochrome P450s are involved in the biosynthesis of various classes of secondary metabolites. To elucidate the biosynthesis of zerumbone, a sesquiterpenoid with multiple potential anticancer pr…
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Altered cross-linking of HSP27 by zerumbone as a novel strategy for overcoming HSP27-mediated radioresistance. Int. J. Radiat. Oncol. Biol. Phys. 79(4) , 1196-205, (2011)
HSP27 or HSP25 negatively regulates apoptosis pathways after radiation or chemotherapeutic agents. Abrogation of HSP27 function may be a candidate target for overcoming radio- and chemoresistance.Zeru…
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Effects of selected food phytochemicals in reducing the toxic actions of TCDD and p,p’-DDT in U937 macrophages. Arch. Toxicol. 84(12) , 957-66, (2010)
To assess the effectiveness of selected food phytochemicals in reducing the toxic effects of the environmental toxicants, 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and p,p’-DDT (DDT), we tested the p…
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(2E,6E,10E)-2,6,9,9-Tetramethyl-2,6,10-cycloundecatrien-1-one |
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(2E,6E,10E)-2,6,9,9-Tetramethylcycloundeca-2,6,10-trien-1-one |
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2,6,10-Cycloundecatrien-1-one, 2,6,9,9-tetramethyl-, (2E,6E,10E)- |
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ZERUMBONE ((2E,6E,10E)-2,6,9,9-TETRAMETHYLCYCLOUNDECA-2,6,10-TRIEN-1-ONE) |
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zerumbone |
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