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苄氟噻嗪

苄氟噻嗪

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?苄氟噻嗪名称


















中文名

苄氟噻嗪
英文名

bendroflumethiazide
中文别名


3-苄基-3,4-二氢-6-(三氟甲基)-2H-1,2,4-苯并噻二嗪-7-磺酰胺-1,1-二氧化物




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3-苄基-3,二氢-6-(三氟甲基)-2H-1,2,4-苯并噻二嗪-7-氨基磺酰-1,1-二氧化物



英文别名
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?苄氟噻嗪生物活性




































描述
苯卓氟甲肼是一种口服利尿剂。苯卓氟甲基噻嗪是一种抗高血压药物。苯卓氟甲基噻嗪在动脉性高血压疾病的研究中具有潜力[1]。
相关类别



存储

请将产品存放在分析证书中的建议条件下。


运输

室温
参考文献

[1]. GRIEBLE HG, et al. Treatment of arterial hypertensive disease with diuretics. I. Effects on blood pressure of bendroflumethiazide, potassium chloride, and spironolactone. Arch Intern Med. 1962;110:26-33.







?苄氟噻嗪物理化学性质













































密度 1.5±0.1 g/cm3
沸点 602.1±65.0 °C at 760 mmHg
熔点 205-207?C
分子式 C15H14F3N3O4S2
分子量 421.415
闪点 318.0±34.3 °C
精确质量 421.037781
PSA 135.12000
LogP 2.07
外观性状 白色固体
蒸汽压 0.0±1.7 mmHg at 25°C
折射率 1.584
储存条件 通风低温干燥
水溶解性 Practically insoluble in water, freely soluble in acetone, soluble in ethanol (96 per cent).






?苄氟噻嗪MSDS







?苄氟噻嗪毒性和生态




苄氟噻嗪毒性英文版






?苄氟噻嗪安全信息






















个人防护装备
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
危险品运输编码 NONH for all modes of transport
WGK德国 2
RTECS号 DK8225000





















?苄氟噻嗪文献28

更多文献














Ultra high performance supercritical fluid chromatography coupled with tandem mass spectrometry for screening of doping agents. I: Investigation of mobile phase and MS conditions.

Anal. Chim. Acta 853 , 637-46, (2014)

The conditions for the analysis of selected doping substances by UHPSFC-MS/MS were optimized to ensure suitable peak shapes and maximized MS responses. A representative mixture of 31 acidic and basic …





Ultra high performance supercritical fluid chromatography coupled with tandem mass spectrometry for screening of doping agents. II: Analysis of biological samples.

Anal. Chim. Acta 853 , 647-59, (2014)

The potential and applicability of UHPSFC-MS/MS for anti-doping screening in urine samples were tested for the first time. For this purpose, a group of 110 doping agents with diverse physicochemical p…





Binding of diuretic antihypertensive bendroflumethiazide to human serum albumin studied by ??F nuclear magnetic resonance method.

Eur. J. Pharm. Sci. 45(1-2) , 195-200, (2012)

Simultaneous specific and nonspecific binding of bendroflumethiazide (BFZ) to human serum albumin (HSA) and concentration profile of BFZ in HSA buffer (pH 7.40) solution were investigated by ??F nucle…









?苄氟噻嗪英文别名














































































2H-1,2,4-Benzothiadiazine-7-sulfonamide, 3,4-dihydro-3-(phenylmethyl)-6-(trifluoromethyl)-, 1,1-dioxide


Pluryl


benzoflumethiazide


3-Benzyl-6-(trifluorométhyl)-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide-1,1-dioxyde


Bendrofluazide


3-benzyl-1,1-dioxo-6-(trifluoromethyl)-3,4-dihydro-2H-1λ<sup>6</sup>,2,4-benzothiadiazine-7-sulfonamide


Naturetin


3,4-Dihydro-3-(phenylmethyl)-6-(trifluoromethyl)-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide


3-Benzyl-3,4-dihydro-7-sulfamyl-6-trifluoromethyl-1,2,4-benzothiadiazine 1,1-Dioxide


3-Benzyl-6-(trifluoromethyl)-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide


Benzydroflumethiazide


Centyl


Benzylrodiuran


Berkozide


bendroflumethiazide


bendroflumethazide


Neo-naclex


Naturine


3-(Phenylmethyl)-6-(trifluoromethyl)-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide


bendroflumetazide


Aprinox


T66 BSWM EM DHJ D1R& HXFFF ISZW


Salures








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