中文名 |
茶苯海明 |
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英文名 |
dimenhydrinate |
中文别名 |
1,3-二甲基-8-氯-3,7-二氢-1H-嘌呤-2,6-二酮 N,N-二甲基-2-(二苯基甲氧基)乙胺 | 1,3-二甲基-8氯-3,7-二氢-1H-嘌呤,6二酮-N,N-二甲基-2-(二苯基甲氧基)乙胺盐 |
英文别名 |
更多 |
描述 |
Dimenhydrinate是一种抗催吐剂, 和抗组胺剂, 用作晕车的补救措施。 |
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相关类别 |
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溶解度 |
体外:
DMSO:≥37mg / mL(78.73 mM) * “≥”表示可溶,但饱和度未知。
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储备液 |
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存储 |
4°C,避光
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运输 |
室温;可能会有所不同 |
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SMILES |
O=C(N1C)N(C)C2=C(NC(Cl)=N2)C1=O.CN(C)CCOC(C3=CC=CC=C3)C4=CC=CC=C4 |
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相关活性 小分子 |
氯雷他定 | 组胺 | 1-[3-[3-(4-氯丙基)丙氧基]丙基]-哌啶盐酸盐 | 西咪替丁 | 蛇床子素 | 富马酸氯马斯汀 | 乙溴替丁 | 1-[(5-氯-1H-吲哚-2-基)羰基]-4-甲基哌嗪 | 法莫替丁 | 盐酸西替利嗪 | 地氯雷他定 | 富马酸酮替芬 | 诺朵腊酸 | 盐酸美克洛嗪 | 扑尔敏 |
沸点 | 343.7?C at 760 mmHg |
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熔点 | 102-107?C |
分子式 | C24H28ClN5O3 |
分子量 | 469.96400 |
闪点 | 101.5?C |
精确质量 | 469.18800 |
PSA | 85.15000 |
LogP | 2.96790 |
外观性状 | 结晶白色粉末 |
水溶解性 | Slightly soluble (0.1-1 g/100 mL at 22 ?C) |
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茶苯海明毒性英文版
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符号 |
GHS07 |
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信号词 |
Warning |
危害声明 |
H302 |
警示性声明 |
P301 + P312 + P330 |
个人防护装备 |
dust mask type N95 (US);Eyeshields;Gloves |
危害码 (欧洲) |
Xn:Harmful |
风险声明 (欧洲) |
R22 |
安全声明 (欧洲) |
22-26-36/37/39-53 |
危险品运输编码 | NONH for all modes of transport |
WGK德国 | 3 |
RTECS号 | XH5082000 |
海关编码 | 2933990090 |
海关编码 | 2933990090 |
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中文概述 | 2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0% |
申报要素 | 品名, 成分含量, 用途, 乌洛托品请注明外观, 6-己内酰胺请注明外观, 签约日期 |
Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
Individualizing oral busulfan dose after using a test dose in patients undergoing hematopoietic stem cell transplantation: pharmacokinetic characterization. Ther. Drug Monit. 37(1) , 66-70, (2015)
Busulfan is an alkylating agent used for conditioning patients undergoing hematopoietic stem cell transplantation with a narrow therapeutic range and highly variable pharmacokinetics. High concentrati…
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Nausea and vomiting in pregnancy: a review of the pathology and compounding opportunities. Int. J. Pharm. Compd. 17(2) , 113-23, (2013)
Nausea and vomiting in pregnancy can have serious adverse effects on the quality of a woman’s life, affecting her occupational, social, and domestic functioning, and her general well-being; therefore,…
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Mechanisms and abuse liability of the anti-histamine dimenhydrinate. Neurosci. Biobehav. Rev. 26(1) , 61-7, (2002)
The over-the-counter anti-emetic dimenhydrinate (DMH) (Gravol or Dramamine) has been reported to be abused for non-medicinal purposes. Street drug users abuse DMH for the acute effects of euphoric sen…
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|
faston |
dromyl |
N-(2-Diphenylmethoxyethyl)-N,N-dimethylammonium 8-chlorotheophyllinate |
8-Chlor-1,3-dimethyl-3,7-dihydro-purin-2,6-dion,Verbindung mit (2-Benzhydryloxy-aethyl)-dimethyl-amin |
gravol |
epha |
EINECS 208-350-8 |
vomexa |
amosyt |
MFCD00054265 |
emedyl |
dramyl |
emes |
Dimenhydrinate |
8-chloro-1,3-dimethyl-3,7-dihydro-purine-2,6-dione,compound with (2-benzhydryloxy-ethyl)-dimethyl-amine |
Dimenhydrinase |
DiMate |