描述 |
Cirsimaritin可以较弱的靶向结合 GABAA 受体上的苯二氮平位点,并拥有抗抑郁、抗焦虑、抗接种等活性。 |
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相关类别 |
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体内研究 |
Cirsimaritin显着降低小鼠的焦虑。氟马西尼(2.5 mg / kg)与salvigenin,rosmanol和cirsimaritin(10 mg / kg)联合给药可降低Cirsimaritin,表明高亲和性苯二氮卓结合位点不参与这些化合物诱导的抗焦虑活性[ 1]。 |
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溶解度 |
体外:
在DMSO中10mM
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储备液 |
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存储 |
请将产品存放在分析证书中的建议条件下。
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运输 |
室温;可能会有所不同 |
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SMILES |
O=C1C=C(C2=CC=C(O)C=C2)OC3=CC(OC)=C(OC)C(O)=C13 |
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参考文献 |
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相关活性 小分子 |
(+)-荷包牡丹碱 | 苦毒浆果[木防已属] | 羧甲基羟胺半盐酸盐 | 利鲁唑 | 巴氯芬 | 巴米沙尼 | (R)-巴氯芬(mM/ml) | 艾替伏辛 | 依托咪酯 | 银杏内酯A | 3′-[5-(1-羟基-1-甲基乙基)-1H-苯并咪唑-1-基]-[1,1'-联苯]-2-甲腈 | 5alpha-孕甾-3alpha-醇-20-酮 | 4-苄氧基苯基异硫氰酸酯 | L-655708 | SAGE-217 |
密度 | 1.4±0.1 g/cm3 |
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沸点 | 563.6±50.0 °C at 760 mmHg |
分子式 | C17H14O6 |
分子量 | 314.289 |
闪点 | 211.5±23.6 °C |
精确质量 | 314.079041 |
PSA | 89.13000 |
LogP | 1.97 |
蒸汽压 | 0.0±1.6 mmHg at 25°C |
折射率 | 1.646 |
储存条件 | ?20°C |
符号 |
GHS06, GHS09 |
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信号词 |
Danger |
危害声明 |
H301-H410 |
警示性声明 |
P273-P301 + P310-P501 |
危害码 (欧洲) |
T,N |
风险声明 (欧洲) |
25-50 |
安全声明 (欧洲) |
45-61 |
危险品运输编码 | UN 2811 6.1 / PGIII |
海关编码 | 2914509090 |
蓟黄素上游产品? 6 | |
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蓟黄素下游产品? 0 |
海关编码 | 2914509090 |
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中文概述 | 2914509090 含其他含氧基的酮. 增值税率:17.0% 退税率:9.0% 监管条件:无 最惠国关税:5.5% 普通关税:30.0% |
申报要素 | 品名, 成分含量, 用途, 丙酮报明包装 |
Summary | HS:2914509090 other ketones with other oxygen function VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0% |
[Studies on flavonoid constituents from herbs of Artemisia ordosica II]. Zhongguo Zhong Yao Za Zhi 31(23) , 1959-61, (2006)
To study the chemical constituents of herbs of Artemisia ordosica.The chemical constituents were isolated and repeatedly purified on silica gel column and the structures were elucidated by the NMR spe…
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[Study on chemical constituents from Incarvillea arguta and their accelerating PC-12 cell differentiation]. Zhongguo Zhong Yao Za Zhi 30(17) , 1335-8, (2005)
To study chemical constituents of Incarvillea arguta and their accelerating PC-12 cell differentiation.The constituents were isolated and repeatedly purified on silica gel column chromatography, and w…
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[Determination of flavonoids in buds of Herba Artemisiae Scopariae by HPLC]. Zhongguo Zhong Yao Za Zhi 30(8) , 591-4, (2005)
To develop a quantitative method for the determination of four flavonoids in buds of Herba Artemisiae Scopariae.The sample was extracted by ultrasonic with ethyl acetate for 30 minutes and separated o…
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5,4′-dihydroxy-6,7-dimethoxyflavone |
5-hydroxy-2-(4-hydroxyphenyl)-6,7-dimethoxychromen-4-one |
Flavone, 4′,5-dihydroxy-6,7-dimethoxy- |
6,7-Dimethoxyscutellarein |
Circimaritin |
7-Methylcapillarisin |
5-Hydroxy-2-(4-hydroxyphenyl)-6,7-dimethoxy-4H-chromen-4-one |
cirsimartin |
5-hydroxy-2-(4-hydroxyphenyl)-6,7-dimethoxy-chromen-4-one |
Scrophulein |
4H-1-Benzopyran-4-one,5-hydroxy-2-(4-hydroxyphenyl)-6,7-dimethoxy |
Skrofulein |
4H-1-Benzopyran-4-one, 5-hydroxy-2-(4-hydroxyphenyl)-6,7-dimethoxy- |
4′,5-Dihydroxy-6,7-dimethoxyflavone |
cirsimaritin |