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蓟黄素

蓟黄素

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?蓟黄素名称
















中文名

蓟黄素
英文名

cirsimaritin
英文别名
更多





?蓟黄素生物活性














































描述
Cirsimaritin可以较弱的靶向结合 GABAA 受体上的苯二氮平位点,并拥有抗抑郁、抗焦虑、抗接种等活性。
相关类别





体内研究

Cirsimaritin显着降低小鼠的焦虑。氟马西尼(2.5 mg / kg)与salvigenin,rosmanol和cirsimaritin(10 mg / kg)联合给药可降低Cirsimaritin,表明高亲和性苯二氮卓结合位点不参与这些化合物诱导的抗焦虑活性[ 1]。
溶解度

体外:

在DMSO中10mM


储备液

1 mM 3.1818 mL 15.9089 mL 31.8177 mL
5 mM 0.6364 mL 3.1818 mL 6.3635 mL
10 mM 0.3182 mL 1.5909 mL 3.1818 mL


存储

请将产品存放在分析证书中的建议条件下。


运输

室温;可能会有所不同
SMILES

O=C1C=C(C2=CC=C(O)C=C2)OC3=CC(OC)=C(OC)C(O)=C13
参考文献

[1]. Abdelhalim A, et al. Antidepressant, Anxiolytic and Antinociceptive Activities of Constituents from Rosmarinus Officinalis. J Pharm Pharm Sci. 2015;18(4):448-59.


相关活性
小分子




(+)-荷包牡丹碱



|

苦毒浆果[木防已属]



|

羧甲基羟胺半盐酸盐



|

利鲁唑



|

巴氯芬



|

巴米沙尼



|

(R)-巴氯芬(mM/ml)



|

艾替伏辛



|

依托咪酯



|

银杏内酯A



|

3′-[5-(1-羟基-1-甲基乙基)-1H-苯并咪唑-1-基]-[1,1'-联苯]-2-甲腈



|

5alpha-孕甾-3alpha-醇-20-酮



|

4-苄氧基苯基异硫氰酸酯



|

L-655708



|

SAGE-217






?蓟黄素物理化学性质





































密度 1.4±0.1 g/cm3
沸点 563.6±50.0 °C at 760 mmHg
分子式 C17H14O6
分子量 314.289
闪点 211.5±23.6 °C
精确质量 314.079041
PSA 89.13000
LogP 1.97
蒸汽压 0.0±1.6 mmHg at 25°C
折射率 1.646
储存条件 ?20°C






?蓟黄素安全信息
































符号

GHS06

GHS09


GHS06, GHS09
信号词
Danger
危害声明
H301-H410
警示性声明
P273-P301 + P310-P501
危害码 (欧洲)
T,N
风险声明 (欧洲)
25-50
安全声明 (欧洲)
45-61
危险品运输编码 UN 2811 6.1 / PGIII
海关编码 2914509090





?蓟黄素合成线路



















?蓟黄素海关















海关编码 2914509090
中文概述 2914509090 含其他含氧基的酮. 增值税率:17.0% 退税率:9.0% 监管条件:无 最惠国关税:5.5% 普通关税:30.0%
申报要素 品名, 成分含量, 用途, 丙酮报明包装
Summary HS:2914509090 other ketones with other oxygen function VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%








?蓟黄素文献13

更多文献














[Studies on flavonoid constituents from herbs of Artemisia ordosica II].

Zhongguo Zhong Yao Za Zhi 31(23) , 1959-61, (2006)

To study the chemical constituents of herbs of Artemisia ordosica.The chemical constituents were isolated and repeatedly purified on silica gel column and the structures were elucidated by the NMR spe…





[Study on chemical constituents from Incarvillea arguta and their accelerating PC-12 cell differentiation].

Zhongguo Zhong Yao Za Zhi 30(17) , 1335-8, (2005)

To study chemical constituents of Incarvillea arguta and their accelerating PC-12 cell differentiation.The constituents were isolated and repeatedly purified on silica gel column chromatography, and w…





[Determination of flavonoids in buds of Herba Artemisiae Scopariae by HPLC].

Zhongguo Zhong Yao Za Zhi 30(8) , 591-4, (2005)

To develop a quantitative method for the determination of four flavonoids in buds of Herba Artemisiae Scopariae.The sample was extracted by ultrasonic with ethyl acetate for 30 minutes and separated o…









?蓟黄素英文别名






















































5,4′-dihydroxy-6,7-dimethoxyflavone


5-hydroxy-2-(4-hydroxyphenyl)-6,7-dimethoxychromen-4-one


Flavone, 4′,5-dihydroxy-6,7-dimethoxy-


6,7-Dimethoxyscutellarein


Circimaritin


7-Methylcapillarisin


5-Hydroxy-2-(4-hydroxyphenyl)-6,7-dimethoxy-4H-chromen-4-one


cirsimartin


5-hydroxy-2-(4-hydroxyphenyl)-6,7-dimethoxy-chromen-4-one


Scrophulein


4H-1-Benzopyran-4-one,5-hydroxy-2-(4-hydroxyphenyl)-6,7-dimethoxy


Skrofulein


4H-1-Benzopyran-4-one, 5-hydroxy-2-(4-hydroxyphenyl)-6,7-dimethoxy-


4′,5-Dihydroxy-6,7-dimethoxyflavone


cirsimaritin








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