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| 描述 |
Danofloxacin 是一种具有口服活性第的三代氟喹诺酮抗菌剂，对大多数革兰氏阴性和革兰氏阳性细菌，支原体和衣原体物种具有广谱的活性，并通过抑制细菌的 DNA 回转酶发挥抗菌作用。Danofloxacinh 可用于牛，猪和鸡呼吸道疾病的研究。 |
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| 相关类别 |
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| SMILES |
O=C(C1=CN(C2CC2)C3=C(C=C(F)C(N4[C@](C5)([H])CN(C)[C@]5([H])C4)=C3)C1=O)O |
| 参考文献 |
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| 密度 | 1.5±0.1 g/cm3 |
|---|---|
| 沸点 | 569.3±50.0 °C at 760 mmHg |
| 熔点 | 268-272?C |
| 分子式 | C19H20FN3O3 |
| 分子量 | 357.379 |
| 闪点 | 298.1±30.1 °C |
| 精确质量 | 357.148865 |
| PSA | 65.78000 |
| LogP | 1.20 |
| 蒸汽压 | 0.0±1.6 mmHg at 25°C |
| 折射率 | 1.679 |
| 水溶解性 | Soluble in water, acetic acid and DMSO |
| 个人防护装备 |
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| 危害码 (欧洲) |
Xn,Xi |
| 风险声明 (欧洲) |
20/21/22-36/37/38 |
| 安全声明 (欧洲) |
22-24/25 |
| 危险品运输编码 | NONH for all modes of transport |
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Multiresidue determination of fluoroquinolones in poultry muscle and kidney according to the regulation 2002/657/EC. A systematic comparison of two different approaches: Liquid chromatography coupled to high-resolution mass spectrometry or tandem mass spectrometry. J. Chromatogr. A. 1379 , 83-91, (2015)
This work involved the optimization and validation of two methods according to the Commission Decision 2002/657/EC directives for determining fluoroquinolones residues in samples of poultry muscle and…
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Simultaneous determination of 38 veterinary antibiotic residues in raw milk by UPLC-MS/MS. Food Chem. 181 , 119-26, (2015)
A selective and rapid method has been developed to determine, simultaneously, 38 veterinary antibiotic residues in raw milk by ultra-high-performance liquid chromatography-tandem mass spectrometry (UP…
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Decay mechanisms of protonated 4-quinolone antibiotics after electrospray ionization and ion activation. J. Am. Soc. Mass Spectrom. 25(11) , 1974-86, (2014)
This study presents a detailed experimental investigation of charge isomers of protonated 4-quinolone antibiotics molecules formed during electrospray ionization (ESI) with proposed dissociation mecha…
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1-Cyclopropyl-6-fluoro-7-[(1S,4S)-5-methyl-2,5-diazabicyclo[2.2.1]hept-2-yl]-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid |
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danofloxacin |
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3-Quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-7-[(1S,4S)-5-methyl-2,5-diazabicyclo[2.2.1]hept-2-yl]-4-oxo- |
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1-Cyclopropyl-6-fluoro-7-[(1S,4S)-5-methyl-2,5-diazabicyclo[2.2.1]hept-2-yl]-4-oxo-1,4-dihydroquinoline-3-carboxylic acid |
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(1S)-1-Cyclopropyl-6-fluoro-1,4-dihydro-7-(5-methyl-2,5-diazabicyclo[2.2.1]hept-2-yl)-4-oxo-3-quinolinecarboxylic acid |
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