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通关藤苷I

通关藤苷I

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?通关藤苷I名称


















中文名

通关藤苷I
英文名

(3β,5α,11α,12β,14β,17α)-12-Acetoxy-3-{[2,6-dideoxy-4-O-(6-deoxy-3-O-methyl-β-D-allopyranosyl)-3-O-methyl-β-D-arabino-hexopyranosyl]oxy}-20-oxo-8,14-epoxypregnan-11-yl benzoate
中文别名


通关藤苷I




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通关藤皂苷I



英文别名
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?通关藤苷I生物活性


































描述
Tenacissoside I 是一种来自 Marsdenia tenacissima 的 C21 甾体,在 M. tenacissima 含量较高。
相关类别



SMILES

C[C@@]([C@@H]([C@@H](OC(C1=CC=CC=C1)=O)[C@]2([H])[C@]34C)OC(C)=O)([C@@H]5C(C)=O)[C@]6(CC5)[C@@]2(CC[C@@]3([H])C[C@@H](O[C@@](O[C@H](C)[C@H]7O[C@@](O[C@H](C)[C@@H](O)[C@H]8OC)([H])[C@@H]8O)([H])C[C@H]7OC)CC4)O6
参考文献

[1]. Zhao C, et al, Metabolic profiling of tenacigenin B, tenacissoside H and tenacissoside I using UHPLC-ESI-Orbitrap MS/MS. Biomed Chromatogr. 2016 Nov;30(11):1757-1765.

[2]. Wang W, et al. Simultaneous quantification of two steroidal glycosides after oral gavage of Marsdenia tenacissima extract in rats using a LC-MS/MS method. Biomed Chromatogr. 2015 Apr;29(4):633-40.







?通关藤苷I物理化学性质



































密度 1.3±0.1 g/cm3
沸点 850.8±65.0 °C at 760 mmHg
分子式 C44H62O14
分子量 814.955
闪点 247.2±27.8 °C
精确质量 814.413940
PSA 178.04000
LogP 5.34
蒸汽压 0.0±0.3 mmHg at 25°C
折射率 1.580
















?通关藤苷I英文别名



























(3β,5α,11α,12β,14β)-12-Acetoxy-3-{[2,6-dideoxy-4-O-(6-deoxy-3-O-methyl-D-allopyranosyl)-3-O-methyl-β-D-arabino-hexopyranosyl]oxy}-20-oxo-8,14-epoxypregnan-11-yl benzoate


Pregnan-20-one, 12-(acetyloxy)-11-(benzoyloxy)-3-[[2,6-dideoxy-4-O-(6-deoxy-3-O-methyl-β-D-allopyranosyl)-3-O-methyl-β-D-arabino-hexopyranosyl]oxy]-8,14-epoxy-, (3β,5α,11α,12β,14be ta,17α)-


Pregnan-20-one, 12-(acetyloxy)-11-(benzoyloxy)-3-[[2,6-dideoxy-4-O-(6-deoxy-3-O-methyl-D-allopyranosyl)-3-O-methyl-β-D-arabino-hexopyranosyl]oxy]-8,14-epoxy-, (3β,5α,11α,12β,14β)-


(1R,3aR,4aS,6aS,8S,10aS,10bS,11S,12S,12aS)-12-acetoxy-1-acetyl-8-(((2R,4R,5R,6R)-5-(((2S,3R,4R,5R,6R)-3,5-dihydroxy-4-methoxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-4-methoxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-10a,12a-dimethyltetradecahydro-1H-cyclopenta[1,2]phenanthro[1,10a-b]oxiren-11-yl benzoate


(3β,5α,11α,12β,14β,17α)-12-Acetoxy-3-{[2,6-dideoxy-4-O-(6-deoxy-3-O-methyl-β-D-allopyranosyl)-3-O-methyl-β-D-arabino-hexopyranosyl]oxy}-20-oxo-8,14-epoxypregnan-11-yl benzoa te


Tenacissoside I








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