中文名 |
[10]-姜酚 |
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英文名 |
[10]-Gingerol |
中文别名 |
10-姜酮醇 | (S)-5-羟基-1-(4-羟基-3-甲氧基苯基)十四烷-3-酮 | 10-姜辣醇 | 10-姜酚 |
英文别名 |
更多 |
描述 |
10-Gingerol 是姜根脂的一种主要刺激性成分,具有抗炎、抗氧化和抗增殖活性。10-Gingerol 能抑制 MDA-MB-231 肿瘤细胞的增殖,其 IC50 值为 12.1 μM。 |
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相关类别 |
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SMILES |
CCCCCCCCC[C@H](O)CC(CCC1=CC=C(O)C(OC)=C1)=O |
参考文献 |
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密度 | 1.0±0.1 g/cm3 |
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沸点 | 499.7±35.0 °C at 760 mmHg |
熔点 | 45 – 46 °C |
分子式 | C21H34O4 |
分子量 | 350.492 |
闪点 | 166.4±19.4 °C |
精确质量 | 350.245697 |
PSA | 66.76000 |
LogP | 4.61 |
蒸汽压 | 0.0±1.3 mmHg at 25°C |
折射率 | 1.513 |
储存条件 | 2-8°C |
水溶解性 | methanol: soluble5mg/mL, clear, colorless |
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[10]-姜酚毒性英文版
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海关编码 | 2914509090 |
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中文概述 | 2914509090 含其他含氧基的酮. 增值税率:17.0% 退税率:9.0% 监管条件:无 最惠国关税:5.5% 普通关税:30.0% |
申报要素 | 品名, 成分含量, 用途, 丙酮报明包装 |
Summary | HS:2914509090 other ketones with other oxygen function VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0% |
Regioselective glucuronidation of gingerols by human liver microsomes and expressed UDP-glucuronosyltransferase enzymes: reaction kinetics and activity correlation analyses for UGT1A9 and UGT2B7. J. Pharm. Pharmacol. 67(4) , 583-96, (2015)
To determine the reaction kinetics for regioselective glucuronidation of gingerols (i.e. 6-, 8- and 10-gingerol) by human liver microsomes and expressed UDP-glucuronosyltransferase (UGT) enzymes, and …
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Identification of serotonin 5-HT1A receptor partial agonists in ginger. Bioorg. Med. Chem. 18 , 3345-51, (2010)
Animal studies suggest that ginger (Zingiber officinale Roscoe) reduces anxiety. In this study, bioactivity-guided fractionation of a ginger extract identified nine compounds that interact with the hu…
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Antiallergic potential on RBL-2H3 cells of some phenolic constituents of Zingiber officinale (ginger). J. Nat. Prod. 72 , 950-3, (2009)
In the present study on five pure phenolic compounds (1-5) isolated from the rhizomes of Zingiber officinale (ginger) and investigated for their antiallergic potency, rat basophilic leukemia (RBL-2H3)…
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(S)- 5-Hydroxy-1-(4-hydroxy-3-methoxyphenyl)-3-tetradecanone |
(5S)-5-Hydroxy-1-(4-hydroxy-3-methoxyphenyl)-3-tetradecanone |
(5s)-5-hydroxy-1-(4-hydroxy-3-methoxyphenyl)tetradecan-3-one |
<10>-Gingerol |
10-Gingerol |
3-Tetradecanone, 5-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-, (5S)- |