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4-(3-(4,4,5,5-四甲基-1,3,2-二氧杂硼烷-2-基)苯基)哌嗪-1-甲酸叔丁酯

4-(3-(4,4,5,5-四甲基-1,3,2-二氧杂硼烷-2-基)苯基)哌嗪-1-甲酸叔丁酯

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?名称
















中文名

3-[4-(叔丁氧基羰基)哌嗪-1-基]苯硼酸频那醇酯
英文名

tert-butyl 4-[3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]piperazine-1-carboxylate
英文别名
更多








?物理化学性质






















分子式 C21H33BN2O4
分子量 388.30900
精确质量 388.25300
PSA 51.24000
LogP 3.04580






?MSDS






MSDS英文版




?合成线路
































tert-butyl 4-(3-(((trifluoromethyl)sulfonyl)oxy)phenyl)piperazine-1-carboxylate结构式

tert-butyl 4-(3…

540752-86-1








联硼酸频那醇酯结构式

联硼酸频那醇酯

73183-34-3




~81%







4-(3-(4,4,5,5-四甲基-1,3,2-二氧杂硼烷-2-基)苯基)哌嗪-1-甲酸叔丁酯结构式

4-(3-(4,4,5,5-四…

540752-87-2


文献：Matasi, Julius J.; Caldwell, John P.; Zhang, Hongtao; Fawzi, Ahmad; Higgins, Guy A.; Cohen-Williams, Mary E.; Varty, Geoffrey B.; Tulshian, Deen B. Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 16 p. 3675 – 3678





联硼酸频那醇酯结构式

联硼酸频那醇酯

73183-34-3








4-(3-溴-苯基)-哌嗪-1-羧酸叔丁酯结构式

4-(3-溴-苯基)-哌嗪-1…

327030-39-7




~92%







4-(3-(4,4,5,5-四甲基-1,3,2-二氧杂硼烷-2-基)苯基)哌嗪-1-甲酸叔丁酯结构式

4-(3-(4,4,5,5-四…

540752-87-2


文献：Castillo, Marcos; Forns, Pilar; Erra, Montse; Mir, Marta; Lopez, Manel; Maldonado, Monica; Orellana, Adelina; Carreno, Cristina; Ramis, Isabel; Miralpeix, Montserrat; Vidal, Bernat Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 17 p. 5419 – 5423





1-Boc-哌嗪结构式

1-Boc-哌嗪

57260-71-6




~%







4-(3-(4,4,5,5-四甲基-1,3,2-二氧杂硼烷-2-基)苯基)哌嗪-1-甲酸叔丁酯结构式

4-(3-(4,4,5,5-四…

540752-87-2


文献：Bioorganic and Medicinal Chemistry Letters, , vol. 15, # 16 p. 3675 – 3678





1-(3-羟基苯基)-哌嗪-4-羧酸叔丁酯结构式

1-(3-羟基苯基)-哌嗪-4…

198627-86-0




~%







4-(3-(4,4,5,5-四甲基-1,3,2-二氧杂硼烷-2-基)苯基)哌嗪-1-甲酸叔丁酯结构式

4-(3-(4,4,5,5-四…

540752-87-2


文献：Bioorganic and Medicinal Chemistry Letters, , vol. 15, # 16 p. 3675 – 3678





tert-butyl 4-(3-((triisopropylsilyl)oxy)phenyl)piperazine-1-carboxylate结构式

tert-butyl 4-(3…

862261-23-2




~%







4-(3-(4,4,5,5-四甲基-1,3,2-二氧杂硼烷-2-基)苯基)哌嗪-1-甲酸叔丁酯结构式

4-(3-(4,4,5,5-四…

540752-87-2


文献：Bioorganic and Medicinal Chemistry Letters, , vol. 15, # 16 p. 3675 – 3678





(3-溴苯氧基)三异丙基硅烷结构式

(3-溴苯氧基)三异丙基硅烷

571202-87-4




~%







4-(3-(4,4,5,5-四甲基-1,3,2-二氧杂硼烷-2-基)苯基)哌嗪-1-甲酸叔丁酯结构式

4-(3-(4,4,5,5-四…

540752-87-2


文献：Bioorganic and Medicinal Chemistry Letters, , vol. 15, # 16 p. 3675 – 3678





1-溴-3-碘苯结构式

1-溴-3-碘苯

591-18-4




~%







4-(3-(4,4,5,5-四甲基-1,3,2-二氧杂硼烷-2-基)苯基)哌嗪-1-甲酸叔丁酯结构式

4-(3-(4,4,5,5-四…

540752-87-2


文献：Bioorganic and Medicinal Chemistry Letters, , vol. 22, # 17 p. 5419 – 5423

















?英文别名

































{3-[4-(tert-butoxycarbonyl)piperazin-1-yl]phenyl}boronic ester


TERT-BUTYL 4-(3-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PHENYL)PIPERAZINE-1-CARBOXYLATE


BM343


3-[4-(N-Boc)piperazin-1-yl]phenylboronic acid pinacol ester


3-[4-(TERT-BUTOXYCARBONYL)PIPERAZIN-1-YL]PHENYLBORONIC ACID PINACOL ESTER


1,1-dimethylethyl 4-[3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-1-piperazinecarboxylate


4-[3-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenyl]-piperazine-1-carboxylic acid tert-butyl ester


3-(4-tert-butoxycarbonylpiperazinyl)phenylboronic acid pinacol ester








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