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4-Chloro-5-sulfamoylanthranilic Acid

4-Chloro-5-sulfamoylanthranilic Acid

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?4-Chloro-5-sulfamoylanthranilic Acid名称














英文名

2-amino-4-chloro-5-sulfamoylbenzoic acid
英文别名
更多








?4-Chloro-5-sulfamoylanthranilic Acid物理化学性质

































密度 1.726g/cm3
沸点 549.2?C at 760mmHg
分子式 C7H7ClN2O4S
分子量 250.65900
闪点 286?C
精确质量 249.98200
PSA 131.86000
LogP 2.63010
折射率 1.665






?4-Chloro-5-sulfamoylanthranilic Acid安全信息


























符号

GHS07


GHS07
信号词
Warning
危害声明
H315-H319-H335
警示性声明
P305 + P351 + P338
危险品运输编码 NONH for all modes of transport
海关编码 2935009090





?4-Chloro-5-sulfamoylanthranilic Acid合成线路


























~51%







4-Chloro-5-sulfamoylanthranilic Acid结构式

4-Chloro-5-sulf…

3086-91-7






文献:NITROMED, INC. Patent: WO2006/55542 A2, 2006 ; Location in patent: Page/Page column 69-70 ; WO 2006/055542 A2





~%







4-Chloro-5-sulfamoylanthranilic Acid结构式

4-Chloro-5-sulf…

3086-91-7






文献:Journal of the American Chemical Society, , vol. 81, p. 5508 Journal of the American Chemical Society, , vol. 82, p. 2731,2733,2734 US2952680 , ; US2910488 , ;





~%







4-Chloro-5-sulfamoylanthranilic Acid结构式

4-Chloro-5-sulf…

3086-91-7






文献:Journal of the American Chemical Society, , vol. 81, p. 5508 Journal of the American Chemical Society, , vol. 82, p. 2731,2733,2734 US2952680 , ; US2910488 , ;





~%







4-Chloro-5-sulfamoylanthranilic Acid结构式

4-Chloro-5-sulf…

3086-91-7






文献:Journal of the American Chemical Society, , vol. 81, p. 5508 Journal of the American Chemical Society, , vol. 82, p. 2731,2733,2734









~29%











4-Chloro-5-sulfamoylanthranilic Acid结构式

4-Chloro-5-sulf…

3086-91-7






文献:Tetrahedron, , vol. 67, # 49 p. 9518 – 9521







?4-Chloro-5-sulfamoylanthranilic Acid上下游产品















4-Chloro-5-sulfamoylanthranilic Acid上游产品? 5

4-Chloro-5-sulfamoylanthranilic Acid下游产品? 1










?4-Chloro-5-sulfamoylanthranilic Acid海关















海关编码 2935009090
中文概述 2935009090 其他磺(酰)胺. 增值税率:17.0% 退税率:9.0% 监管条件:无 最惠国关税:6.5% 普通关税:35.0%
申报要素 品名, 成分含量, 用途
Summary 2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%








?4-Chloro-5-sulfamoylanthranilic Acid文献10

更多文献














The use of HPLC to elucidate the metabolism and urinary excretion of furosemide and its metabolic products.

Acta Pharmacol. Toxicol. (Copenh.) 49(3) , 223-9, (1981)

Three principles for the use of HPLC with spectrophotometric detection to determine the concentration of furosemide and of 4-chloro-5-sulfamoyl anthranilic acid (CSA) were studied. A reversed phase mi…





The binding of furosemide to serum proteins in elderly patients: displacing effect of phenprocoumon.

Acta Pharmacol. Toxicol. (Copenh.) 47(3) , 202-7, (1980)

The percentual binding of furosemide (5 micrograms/ml) was slightly but significantly lower in serum from elderly patients than in serum from normal blood donors (96.5 +/- 0.7 versus 97.9 +/- 0.3). A …





Furosemide accelerates gentamicin accumulation in cultured renal cells (LLC-PK1 cells).

Nephron 53(2) , 138-41, (1989)

Furosemide is known to potentiate gentamicin nephrotoxicity. The mechanism of potentiation is unclear. In our previous studies, we demonstrated that furosemide enhanced gentamicin accumulation in rabb…









?4-Chloro-5-sulfamoylanthranilic Acid英文别名







































4-Chloro-5-sulfamoylanthranilic acid


2-AMINO-5-AMINOSULFONYL-4-CHLOROBENZOIC ACID


4-chloro-5-sulphamoyl anthranilic acid


Desfurylmethylfurosemide


Saluamine


2-amino-4-chloro-5-sulfamoyl-benzoic acid


Furosemide Related Compound B


EINECS 221-408-7


4-chloro-5-sulfamoyl-anthranilic acid


4-Chloro-5-sulfanilanthranilic acid








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