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(S)-2-(5-溴-1H-咪唑-2-基)-吡咯烷-1-羧酸叔丁酯

(S)-2-(5-溴-1H-咪唑-2-基)-吡咯烷-1-羧酸叔丁酯

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?名称
















中文名

(S)-2-(5-溴-1H-咪唑-2-基)-吡咯烷-1-羧酸叔丁酯
英文名

tert-butyl (2S)-2-(5-bromo-1H-imidazol-2-yl)pyrrolidine-1-carboxylate
英文别名
更多








?物理化学性质



































密度 1.4±0.1 g/cm3
沸点 469.3±35.0 °C at 760 mmHg
分子式 C12H18BrN3O2
分子量 316.194
闪点 237.6±25.9 °C
精确质量 315.058228
PSA 58.22000
LogP 1.65
蒸汽压 0.0±1.2 mmHg at 25°C
折射率 1.567






?安全信息
















海关编码 2933990090





?合成线路





























~30%







(S)-2-(5-溴-1H-咪唑-2-基)-吡咯烷-1-羧酸叔丁酯结构式

(S)-2-(5-溴-1H-咪…

1007882-59-8






文献:TIBOTEC PHARMACEUTICALS; VANDYCK, Koen; LAST, Stefaan Julien; HOUPIS, Ioannis Nicolaos; RABOISSON, Pierre Jean-Marie Bernard Patent: WO2011/54834 A1, 2011 ; Location in patent: Page/Page column 35 ;





~%







(S)-2-(5-溴-1H-咪唑-2-基)-吡咯烷-1-羧酸叔丁酯结构式

(S)-2-(5-溴-1H-咪…

1007882-59-8






文献:MERCK SHARP and DOHME CORP.; COBURN, Craig A.; WU, Hao; HU, Bin; ZHONG, Bin; WANG, Dahai; XU, Zaixu; SUN, Fei; JI, Tao; DAN, Zhigang Patent: WO2012/3642 A1, 2012 ; Location in patent: Example 3 ;





~%







(S)-2-(5-溴-1H-咪唑-2-基)-吡咯烷-1-羧酸叔丁酯结构式

(S)-2-(5-溴-1H-咪…

1007882-59-8






文献:MERCK SHARP and DOHME CORP.; COBURN, Craig A.; WU, Hao; HU, Bin; ZHONG, Bin; WANG, Dahai; XU, Zaixu; SUN, Fei; JI, Tao; DAN, Zhigang Patent: WO2012/3642 A1, 2012 ;





~%







(S)-2-(5-溴-1H-咪唑-2-基)-吡咯烷-1-羧酸叔丁酯结构式

(S)-2-(5-溴-1H-咪…

1007882-59-8






文献:MERCK SHARP and DOHME CORP.; COBURN, Craig A.; WU, Hao; HU, Bin; ZHONG, Bin; WANG, Dahai; XU, Zaixu; SUN, Fei; JI, Tao; DAN, Zhigang Patent: WO2012/3642 A1, 2012 ;





~%







(S)-2-(5-溴-1H-咪唑-2-基)-吡咯烷-1-羧酸叔丁酯结构式

(S)-2-(5-溴-1H-咪…

1007882-59-8






文献:TIBOTEC PHARMACEUTICALS; VANDYCK, Koen; LAST, Stefaan Julien; HOUPIS, Ioannis Nicolaos; RABOISSON, Pierre Jean-Marie Bernard Patent: WO2011/54834 A1, 2011 ;




(S)-2-(5-溴-1H-咪唑-2-基)-吡咯烷-1-羧酸叔丁酯结构式

(S)-2-(5-溴-1H-咪…

1007882-59-8





~%







(S)-2-(5-溴-1H-咪唑-2-基)-吡咯烷-1-羧酸叔丁酯结构式

(S)-2-(5-溴-1H-咪…

1007882-59-8






文献:MERCK SHARP and DOHME CORP.; COBURN, Craig A.; WU, Hao; HU, Bin; ZHONG, Bin; WANG, Dahai; XU, Zaixu; SUN, Fei; JI, Tao; DAN, Zhigang Patent: WO2012/3642 A1, 2012 ;















?海关















海关编码 2933990090
中文概述 2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素 品名, 成分含量, 用途, 乌洛托品请注明外观, 6-己内酰胺请注明外观, 签约日期
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%










?英文别名




































PYR239


2(S)-tert-butyl 2-(4-bromo-1H-imidazol-2-yl)pyrrolidine-1-carboxylate


1-Pyrrolidinecarboxylic acid,2-(5-bromo-1H-imidazol-2-yl)-,1,1-dimethylethyl ester,(2S)


1-Pyrrolidinecarboxylic acid, 2-(5-bromo-1H-imidazol-2-yl)-, 1,1-dimethylethyl ester, (2S)-


2-Methyl-2-propanyl (2S)-2-(4-bromo-1H-imidazol-2-yl)-1-pyrrolidinecarboxylate


(S)-tert-butyl 2-(4-bromo-1H-imidazol-2-yl)pyrrolidine-1-carboxylate


(S)-2-(4-bromo-1H-imidazol-2-yl)pyrrolidine-1-carboxylic acid tert-butyl ester


(S)-tert-Butyl 2-(5-bromo-1H-imidazol-2-yl)pyrrolidine-1-carboxylate


tert-butyl 2-(5-bromo-1H-imidazol-2-yl)pyrrolidine-1-carboxylate








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